SAV1 抗体 (AA 300-383)
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- 抗原 See all SAV1 抗体
- SAV1 (Salvador Homolog 1 (SAV1))
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抗原表位
- AA 300-383
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适用
- 人
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This SAV1 antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunoprecipitation (IP)
- 原理
- Mouse monoclonal antibody raised against a partial recombinant SAV1.
- 序列
- HTAEIPDWLQ VYARAPVKYD HILKWELFQL ADLDTYQGML KLLFMKELEQ IVKMYEAYRQ ALLTELENRK QRQQWYAQQH GKNF
- 交叉反应
- 人
- 产品特性
- Antibody Reactive Against Recombinant Protein.
- 免疫原
- SAV1 (NP_068590, 300 a.a. ~ 383 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
- 克隆位点
- 3B2
- 亚型
- IgG2a
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- 应用备注
- Optimal working dilution should be determined by the investigator.
- 限制
- 仅限研究用
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- 缓冲液
- In 1x PBS, pH 7.4
- 注意事项
- Aliquot to avoid repeated freezing and thawing.
- 储存条件
- -20 °C
- 储存方法
- Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Kidney-specific knockout of Sav1 in the mouse promotes hyperproliferation of renal tubular epithelium through suppression of the Hippo pathway." in: The Journal of pathology, Vol. 239, Issue 1, pp. 97-108, (2016) (PubMed).
: "Hippo signaling mediates proliferation, invasiveness, and metastatic potential of clear cell renal cell carcinoma." in: Translational oncology, Vol. 7, Issue 2, pp. 309-21, (2014) (PubMed).
: "Mammalian ste20-like kinase and SAV1 promote 3T3-L1 adipocyte differentiation by activation of PPAR?." in: PLoS ONE, Vol. 7, Issue 1, pp. e30983, (2012) (PubMed).
: "Screening of binding proteins that interact with human Salvador 1 in a human fetal liver cDNA library by the yeast two-hybrid system." in: Molecular biology reports, Vol. 39, Issue 8, pp. 8225-30, (2012) (PubMed).
: "LATS2 is a tumor suppressor gene of malignant mesothelioma." in: Cancer research, Vol. 71, Issue 3, pp. 873-83, (2011) (PubMed).
: "Components of the Hippo pathway cooperate with Nek2 kinase to regulate centrosome disjunction." in: Nature cell biology, Vol. 12, Issue 12, pp. 1166-76, (2010) (PubMed).
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Kidney-specific knockout of Sav1 in the mouse promotes hyperproliferation of renal tubular epithelium through suppression of the Hippo pathway." in: The Journal of pathology, Vol. 239, Issue 1, pp. 97-108, (2016) (PubMed).
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- 抗原
- SAV1 (Salvador Homolog 1 (SAV1))
- 别名
- SAV1 (SAV1 产品)
- 别名
- SAV antibody, WW45 antibody, WWP4 antibody, 1700040G09Rik antibody, Salv antibody, Sav antibody, Wwp3 antibody, Wwp4 antibody, salvador family WW domain containing protein 1 antibody, salvador family WW domain containing 1 antibody, SAV1 antibody, Sav1 antibody
- 背景
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Full Gene Name: salvador homolog 1 (Drosophila)
Synonyms: SAV,WW45,WWP4 - 基因ID
- 60485
- NCBI登录号
- NM_021818
- 途径
- Stem Cell Maintenance
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