Ubiquilin 2 抗体 (AA 555-624)
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- 抗原 See all Ubiquilin 2 (UBQLN2) 抗体
- Ubiquilin 2 (UBQLN2)
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抗原表位
- AA 555-624
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适用
- 人
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This Ubiquilin 2 antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA, Immunofluorescence (IF)
- 原理
- Mouse monoclonal antibody raised against a partial recombinant UBQLN2.
- 序列
- PNQQFIQQMV QALAGANAPQ LPNPEVRFQQ QLEQLNAMGF LNREANLQAL IATGGDINAA IERLLGSQPS
- 交叉反应
- 人, 小鼠, 大鼠
- 产品特性
- Antibody Reactive Against Recombinant Protein.
- 免疫原
- UBQLN2 (NP_038472, 555 a.a. ~ 624 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
- 克隆位点
- 5F5
- 亚型
- IgG2a
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- 应用备注
- Optimal working dilution should be determined by the investigator.
- 限制
- 仅限研究用
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- 缓冲液
- In 1x PBS, pH 7.4
- 注意事项
- Aliquot to avoid repeated freezing and thawing.
- 储存条件
- -20 °C
- 储存方法
- Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Marked Involvement of the Striatal Efferent System in TAR DNA-Binding Protein 43 kDa-Related Frontotemporal Lobar Degeneration and Amyotrophic Lateral Sclerosis." in: Journal of neuropathology and experimental neurology, (2016) (PubMed).
: "Drosha inclusions are new components of dipeptide-repeat protein aggregates in FTLD-TDP and ALS C9orf72 expansion cases." in: Journal of neuropathology and experimental neurology, Vol. 74, Issue 4, pp. 380-7, (2015) (PubMed).
: "Differential recruitment of UBQLN2 to nuclear inclusions in the polyglutamine diseases HD and SCA3." in: Neurobiology of disease, Vol. 82, pp. 281-8, (2015) (PubMed).
: "Ubiquilin-1 immunoreactivity is concentrated on Hirano bodies and dystrophic neurites in Alzheimer's disease brains." in: Neuropathology and applied neurobiology, Vol. 39, Issue 7, pp. 817-30, (2014) (PubMed).
: "Lower motor neuron involvement in TAR DNA-binding protein of 43 kDa-related frontotemporal lobar degeneration and amyotrophic lateral sclerosis." in: JAMA neurology, Vol. 71, Issue 2, pp. 172-9, (2014) (PubMed).
: "C9ORF72, implicated in amytrophic lateral sclerosis and frontotemporal dementia, regulates endosomal trafficking." in: Human molecular genetics, Vol. 23, Issue 13, pp. 3579-95, (2014) (PubMed).
: "C9ORF72 repeat-associated non-ATG-translated polypeptides are distributed independently of TDP-43 in a Japanese patient with c9ALS." in: Neuropathology and applied neurobiology, Vol. 40, Issue 6, pp. 783-8, (2014) (PubMed).
: "Tau pathology in frontotemporal lobar degeneration with C9ORF72 hexanucleotide repeat expansion." in: Acta neuropathologica, Vol. 125, Issue 2, pp. 289-302, (2013) (PubMed).
: "Progressive amnestic dementia, hippocampal sclerosis, and mutation in C9ORF72." in: Acta neuropathologica, Vol. 126, Issue 4, pp. 545-54, (2013) (PubMed).
: "Pattern of ubiquilin pathology in ALS and FTLD indicates presence of C9ORF72 hexanucleotide expansion." in: Acta neuropathologica, Vol. 123, Issue 6, pp. 825-39, (2012) (PubMed).
: "p62 positive, TDP-43 negative, neuronal cytoplasmic and intranuclear inclusions in the cerebellum and hippocampus define the pathology of C9orf72-linked FTLD and MND/ALS." in: Acta neuropathologica, Vol. 122, Issue 6, pp. 691-702, (2011) (PubMed).
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Marked Involvement of the Striatal Efferent System in TAR DNA-Binding Protein 43 kDa-Related Frontotemporal Lobar Degeneration and Amyotrophic Lateral Sclerosis." in: Journal of neuropathology and experimental neurology, (2016) (PubMed).
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- 抗原
- Ubiquilin 2 (UBQLN2)
- 别名
- UBQLN2 (UBQLN2 产品)
- 别名
- ALS15 antibody, CHAP1 antibody, DSK2 antibody, N4BP4 antibody, PLIC2 antibody, Chap1 antibody, Dsk2 antibody, HRIHFB2157 antibody, Plic-2 antibody, Plic2 antibody, RGD1563566 antibody, UBQLN2 antibody, ubiquilin 2 antibody, UBQLN2 antibody, Ubqln2 antibody
- 背景
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Full Gene Name: ubiquilin 2
Synonyms: CHAP1,CHAP1/DSK2,Dsk2,HRIHFB2157,LIC-2,N4BP4,PLIC-2,PLIC2,RIHFB2157 - 基因ID
- 29978
- NCBI登录号
- NM_013444
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