TRIB2 抗体 (AA 254-343)
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- 抗原 See all TRIB2 抗体
- TRIB2 (Tribbles Pseudokinase 2 (TRIB2))
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抗原表位
- AA 254-343
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适用
- 人
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This TRIB2 antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), RNA Interference (RNAi)
- 原理
- Mouse monoclonal antibody raised against a partial recombinant TRIB2.
- 序列
- FHDIEPSSLF SKIRRGQFNI PETLSPKAKC LIRSILRREP SERLTSQEIL DHPWFSTDFS VSNSAYGAKE VSDQLVPDVN MEENLDPFFN
- 交叉反应
- 人
- 产品特性
- Antibody Reactive Against Recombinant Protein.
- 免疫原
- TRIB2 (NP_067675, 254 a.a. ~ 343 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
- 克隆位点
- 1B1
- 亚型
- IgG2b
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- 应用备注
- Optimal working dilution should be determined by the investigator.
- 限制
- 仅限研究用
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- 缓冲液
- In 1x PBS, pH 7.4
- 注意事项
- Aliquot to avoid repeated freezing and thawing.
- 储存条件
- -20 °C
- 储存方法
- Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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TRIB2 inhibits Wnt/?-Catenin/TCF4 signaling through its associated ubiquitin E3 ligases, ?-TrCP, COP1 and Smurf1, in liver cancer cells." in: FEBS letters, Vol. 588, Issue 23, pp. 4334-41, (2014) (PubMed).
: "Impaired phosphorylation and ubiquitination by p70 S6 kinase (p70S6K) and Smad ubiquitination regulatory factor 1 (Smurf1) promote tribbles homolog 2 (TRIB2) stability and carcinogenic property in ..." in: The Journal of biological chemistry, Vol. 288, Issue 47, pp. 33667-81, (2013) (PubMed).
: "Ubiquitin E3 ligase SCF(?-TRCP) regulates TRIB2 stability in liver cancer cells." in: Biochemical and biophysical research communications, Vol. 441, Issue 3, pp. 555-9, (2013) (PubMed).
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TRIB2 inhibits Wnt/?-Catenin/TCF4 signaling through its associated ubiquitin E3 ligases, ?-TrCP, COP1 and Smurf1, in liver cancer cells." in: FEBS letters, Vol. 588, Issue 23, pp. 4334-41, (2014) (PubMed).
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- 抗原
- TRIB2 (Tribbles Pseudokinase 2 (TRIB2))
- 别名
- TRIB2 (TRIB2 产品)
- 别名
- TRIB2 antibody, Trb2 antibody, Xtrbl antibody, gs3955 antibody, c5fw antibody, trb2 antibody, xtrb2 antibody, TRB2 antibody, C5FW antibody, GS3955 antibody, TRB-2 antibody, AW319517 antibody, RGD1564451 antibody, tribbles pseudokinase 2 antibody, tribbles pseudokinase 2 S homeolog antibody, TRIB2 antibody, trib2 antibody, trib2.S antibody, Trib2 antibody
- 背景
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Full Gene Name: tribbles homolog 2 (Drosophila)
Synonyms: C5FW,GS3955,TRB2 - 基因ID
- 28951
- NCBI登录号
- NM_021643
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