ALDH7A1
适用: 人, 小鼠, 大鼠
IF
宿主: 兔
Polyclonal
unconjugated
应用备注
Western blot: 0.5-1 μg/mL,IHC (FFPE): 1-2 μg/mL
限制
仅限研究用
缓冲液
0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
储存条件
-20 °C
储存方法
After reconstitution, the ALDH7A1 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
抗原
ALDH7A1
(Aldehyde Dehydrogenase 7 Family, Member A1 (ALDH7A1))
atq1 antibody, ALDH7A1 antibody, ATQ1 antibody, EPD antibody, PDE antibody, antiquitin antibody, ATQ antibody, wu:fi34d12 antibody, wu:fi35e06 antibody, Atq1 antibody, D18Wsu181e antibody, aldehyde dehydrogenase 7 family member A1 antibody, aldehyde dehydrogenase 7 family member A1 L homeolog antibody, aldehyde dehydrogenase 7 family, member A1 antibody, aldehyde dehydrogenase family 7, member A1 antibody, ALDH7A1 antibody, aldh7a1 antibody, aldh7a1.L antibody, Aldh7a1 antibody
背景
Aldehyde dehydrogenase 7 family, member A1, also known as ALDH7A1 or antiquitin, is an enzyme that in humans is encoded by the ALDH7A1 gene. The protein encoded by this gene is a member of subfamily 7 in the aldehyde dehydrogenase gene family. These enzymes are thought to play a major role in the detoxification of aldehydes generated by alcohol metabolism andlipid peroxidation. This particular member has homology to a previously described protein from the green garden pea, the 26g pea turgor protein. It is also involved in lysine catabolism that is known to occur in the mitochondrial matrix. Recent reports show that this protein is found both in the cytosol and the mitochondria, and the two forms likely arise from the use of alternative translation initiation sites. An additional variant encoding a different isoform has also been found for this gene. Mutations in this gene are associated with pyridoxine-dependent epilepsy. Several related pseudogenes have also been identified.