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WWP1 抗体 (AA 152-260)

WWP1 适用: 人 WB, ELISA, IP, IF, IHC (p) 宿主: 小鼠 Monoclonal 1A7 unconjugated
产品编号 ABIN564794
发货至: 中国
  • 抗原 See all WWP1 抗体
    WWP1 (WW Domain Containing E3 Ubiquitin Protein Ligase 1 (WWP1))
    抗原表位
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 152-260
    适用
    • 24
    • 6
    • 4
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    宿主
    • 21
    • 4
    小鼠
    克隆类型
    • 22
    • 3
    单克隆
    标记
    • 18
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This WWP1 antibody is un-conjugated
    应用范围
    • 15
    • 7
    • 5
    • 4
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunoprecipitation (IP), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    原理
    Mouse monoclonal antibody raised against a partial recombinant WWP1.
    序列
    CSSSPTIEIQ ENGDALHENG EPSARTTARL AVEGTNGIDN HVPTSTLVQN SCCSYVVNGD NTPSSPSQVA ARPKNTPAPK PLASEPADDT VNGESSSFAP TDNASVTGT
    交叉反应
    产品特性
    Antibody Reactive Against Recombinant Protein.
    免疫原
    WWP1 (NP_008944, 152 a.a. ~ 260 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
    克隆位点
    1A7
    亚型
    IgG2a
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 缓冲液
    In 1x PBS, pH 7.4
    注意事项
    Aliquot to avoid repeated freezing and thawing.
    储存条件
    -20 °C
    储存方法
    Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
  • Basheer, Harris, Mentrup, Abreha, Thames, Lea, Swing, Copeland, Jenkins, Price, Matesic: "Cardiomyocyte-specific overexpression of the ubiquitin ligase Wwp1 contributes to reduction in Connexin 43 and arrhythmogenesis." in: Journal of molecular and cellular cardiology, Vol. 88, pp. 1-13, (2015) (PubMed).

    Cheng, Cao, Yuan, Li, Tong: "Knockdown of WWP1 inhibits growth and induces apoptosis in hepatoma carcinoma cells through the activation of caspase3 and p53." in: Biochemical and biophysical research communications, Vol. 448, Issue 3, pp. 248-54, (2014) (PubMed).

    Chaudhary, Maddika: "WWP2-WWP1 ubiquitin ligase complex coordinated by PPM1G maintains the balance between cellular p73 and ?Np73 levels." in: Molecular and cellular biology, Vol. 34, Issue 19, pp. 3754-64, (2014) (PubMed).

    Cao, Xue, Han, Ma, Chen, Tong: "WW domain-containing E3 ubiquitin protein ligase 1 (WWP1) delays cellular senescence by promoting p27(Kip1) degradation in human diploid fibroblasts." in: The Journal of biological chemistry, Vol. 286, Issue 38, pp. 33447-56, (2011) (PubMed).

    Peschiaroli, Scialpi, Bernassola, El Sherbini, Melino: "The E3 ubiquitin ligase WWP1 regulates ?Np63-dependent transcription through Lys63 linkages." in: Biochemical and biophysical research communications, Vol. 402, Issue 2, pp. 425-30, (2010) (PubMed).

    Edwards, Clowes, Tsang, Connell, Sanderson, Luzio, Reid: "Endogenous spartin (SPG20) is recruited to endosomes and lipid droplets and interacts with the ubiquitin E3 ligases AIP4 and AIP5." in: The Biochemical journal, Vol. 423, Issue 1, pp. 31-9, (2009) (PubMed).

  • 抗原
    WWP1 (WW Domain Containing E3 Ubiquitin Protein Ligase 1 (WWP1))
    别名
    WWP1 (WWP1 产品)
    别名
    AIP5 antibody, Tiul1 antibody, hSDRP1 antibody, 8030445B08Rik antibody, SDRP1 antibody, WWP1 antibody, aip5 antibody, tiul1 antibody, hsdrp1 antibody, WW domain containing E3 ubiquitin protein ligase 1 antibody, WWP1 antibody, Wwp1 antibody, wwp1 antibody
    背景
    Full Gene Name: WW domain containing E3 ubiquitin protein ligase 1
    Synonyms: AIP5,DKFZp434D2111,Tiul1,hSDRP1
    基因ID
    11059
    NCBI登录号
    NM_007013
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