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- 抗原 See all ADO 抗体
- ADO (2-Aminoethanethiol (Cysteamine) Dioxygenase (ADO))
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适用
- 人, 小鼠, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This ADO antibody is un-conjugated
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应用范围
- Western Blotting (WB), Flow Cytometry (FACS)
- 纯化方法
- Antigen affinity purified
- 免疫原
- Amino acids E49-E261 from the human protein were used as the immunogen for the ADO antibody.
- 亚型
- IgG
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anti-2-Aminoethanethiol (Cysteamine) Dioxygenase (ADO) antibody
ADO 适用: 人, 小鼠 ELISA, WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-2-Aminoethanethiol (Cysteamine) Dioxygenase (ADO) (AA 137-270) antibodyADO 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-2-Aminoethanethiol (Cysteamine) Dioxygenase (ADO) (AA 206-233), (C-Term) antibodyADO 适用: 人, 小鼠 WB, FACS 宿主: 兔 Polyclonal RB30095 unconjugated
anti-2-Aminoethanethiol (Cysteamine) Dioxygenase (ADO) (AA 206-233), (C-Term) antibodyADO 适用: 人, 小鼠 WB, EIA 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- Western blot: 0.5-1 μg/mL,FACS: 1-3 μg/10^6 cells
- 限制
- 仅限研究用
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- 缓冲液
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
- 储存条件
- -20 °C
- 储存方法
- After reconstitution, the ADO antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
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- 抗原
- ADO (2-Aminoethanethiol (Cysteamine) Dioxygenase (ADO))
- 别名
- ADO / 2-Aminoethanethiol dioxygenase (ADO 产品)
- 别名
- C10orf22 antibody, Gm237 antibody, RGD1308233 antibody, wu:fc32g01 antibody, wu:fc52c12 antibody, zgc:101580 antibody, 2-aminoethanethiol dioxygenase antibody, 2-aminoethanethiol (cysteamine) dioxygenase antibody, 2-aminoethanethiol (cysteamine) dioxygenase a antibody, ADO antibody, Ado antibody, LOC100351598 antibody, adoa antibody
- 背景
- Human thiol dioxygenases include cysteine dioxygenase (CDO) and cysteamine (2-aminoethanethiol) dioxygenase (ADO). CDO adds 2 oxygen atoms to free cysteine, whereas ADO adds 2 oxygen atoms to free cysteamine to form hypotaurine. It is demonstrated that mouse Ado has strong and specific dioxygenase activity in vitro towards cysteamine but not cysteine. Recombinant Ado was shown to bind iron. Overexpression of Ado in HepG2/C3A cells increased the production of hypotaurine from cysteamine. Similar results were found with human ADO. When endogenous expression of ADO was reduced by RNA-mediated interference, hypotaurine production decreased. It is also noted that the demonstration of high levels of ADO in brain challenges the previous assumption that most of the taurine in the brain is a consequence of CDO activity.
- UniProt
- Q96SZ5
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