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METTL14 抗体 (AA 2-36)

METTL14 适用: 人, 小鼠 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN5647669
发货至: 中国
  • 抗原 See all METTL14 抗体
    METTL14 (Methyltransferase Like 14 (METTL14))
    抗原表位
    • 15
    • 6
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 2-36
    适用
    • 28
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    人, 小鼠
    宿主
    • 27
    • 1
    克隆类型
    • 28
    多克隆
    标记
    • 10
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This METTL14 antibody is un-conjugated
    应用范围
    • 22
    • 13
    • 13
    • 8
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    Western Blotting (WB)
    交叉反应 (详细)
    Expected species reactivity: Bovine
    纯化方法
    Antigen affinity purified
    免疫原
    A portion of amino acids 2-36 from the N-terminal region of the human protein was used as the immunogen for the METTL14 antibody.
    亚型
    Ig Fraction
    Top Product
    Discover our top product METTL14 Primary Antibody
  • 应用备注
    The stated application concentrations are suggested starting points. Titration of the METTL14 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western Blot: 1:2000
    限制
    仅限研究用
  • 缓冲液
    In 1X PBS, pH 7.4, with 0.09 % sodium azide
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Aliquot the METTL14 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
  • 抗原
    METTL14 (Methyltransferase Like 14 (METTL14))
    别名
    METTL14 (METTL14 产品)
    别名
    RGD1304822 antibody, G430022H21Rik antibody, mKIAA1627 antibody, zgc:77296 antibody, methyltransferase like 14 antibody, methyltransferase like 14 L homeolog antibody, Mettl14 antibody, mettl14.L antibody, METTL14 antibody, mettl14 antibody
    背景
    N6-adenosine-methyltransferase subunit METTL14 is an N6-methyltransferase that methylates adenosine residues of some mRNAs and acts as a regulator of the circadian clock and self-renewal of embryonic stem cells. N6-methyladenosine (m6A), which takes place at the 5'-[AG]GAC-3' consensus sites of some mRNAs, plays a role in the efficiency of mRNA splicing and processing and mRNA stability. M6A regulates the length of the circadian clock: acts as a early pace-setter in the circadian loop M6A also acts as a regulator of mRNA stability: in embryonic stem cells (ESCs), m6A methylation of mRNAs encoding developmental regulators, results in transcript destabilization, maintaining the groung state of ESCs, thereby promoting self-renewal of ESCs.
    UniProt
    Q9HCE5
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