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KIT Ligand 抗体

KITLG 适用: 人, 小鼠, 大鼠 WB, IHC (p), ELISA (Capture) 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN5647180
发货至: 中国
  • 抗原 See all KIT Ligand (KITLG) 抗体
    KIT Ligand (KITLG)
    适用
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    人, 小鼠, 大鼠
    宿主
    • 111
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    克隆类型
    • 112
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    多克隆
    标记
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    This KIT Ligand antibody is un-conjugated
    应用范围
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    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), ELISA (Capture)
    纯化方法
    Antigen affinity purified
    免疫原
    A recombinant human protein corresponding to amino acids E26-A190 was used as the immunogen for the SCF antibody.
    亚型
    IgG
    Top Product
    Discover our top product KITLG Primary Antibody
  • 应用备注
    Optimal dilution of the SCF antibody should be determined by the researcher.\. Western Blot: 0.5-1 μg/mL,IHC (FFPE): 1-2 μg/mL,ELISA (Capture, human recombinant protein): 0.1-0.5 μg/mL (BSA-free format available)
    限制
    仅限研究用
  • 缓冲液
    0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
    储存条件
    -20 °C
    储存方法
    After reconstitution, the SCF antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
  • 抗原
    KIT Ligand (KITLG)
    别名
    SCF / KITLG (KITLG 产品)
    别名
    Xkl-1 antibody, Xsl antibody, Xsl-1 antibody, Xsl-2 antibody, steel antibody, KITLG antibody, SCF antibody, kitl antibody, kl-1 antibody, mgf antibody, scf antibody, FPH2 antibody, KL-1 antibody, Kitl antibody, MGF antibody, SF antibody, SHEP7 antibody, Clo antibody, Con antibody, Gb antibody, Kitlg antibody, Mgf antibody, SLF antibody, Sl antibody, blz antibody, contrasted antibody, 710-712 antibody, CSF antibody, KITL antibody, KIT ligand L homeolog antibody, KIT ligand antibody, kit ligand antibody, kitlg.L antibody, KITLG antibody, kitlg antibody, Kitl antibody, Kitlg antibody
    背景
    Stem Cell Factor (also known as SCF, kit-ligand, KL, or steel factor) is a cytokine that binds to the c-Kit receptor (CD117). The SCF gene is mapped to 12q21.32. SCF can exist both as a transmembrane protein and a soluble protein. This cytokine plays an important role in hematopoiesis (formation of blood cells), spermatogenesis, and melanogenesis. SCF may be used along with other cytokines to culture HSCs and hematopoietic progenitors. The expansion of these cells ex-vivo (outside the body) would allow advances in bone-marrow transplantation, in which HSCs are transferred to a patient to re-establish blood formation. One of the problems of injecting SCF for therapeutic purposes is that SCF activates mast cells. The injection of SCF has been shown to cause allergic-like symptoms and the proliferation of mast cells and melanocytes.
    UniProt
    P21583
    途径
    RTK signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway
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