YAP1 抗体 (AA 53-161)
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- 抗原 See all YAP1 抗体
- YAP1 (Yes-Associated Protein 1 (YAP1))
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抗原表位
- AA 53-161
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适用
- 人
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This YAP1 antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- 原理
- Mouse monoclonal antibody raised against a partial recombinant YAP1.
- 序列
- QIVHVRGDSE TDLEALFNAV MNPKTANVPQ TVPMRLRKLP DSFFKPPEPK SHSRQASTDA GTAGALTPQH VRAHSSPASL QLGAVSPGTL TPTGVVSGPA ATPTAQHLR
- 交叉反应
- 人, 小鼠
- 产品特性
- Antibody Reactive Against Recombinant Protein.
- 免疫原
- YAP1 (NP_006097, 53 a.a. ~ 161 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
- 克隆位点
- 2F12
- 亚型
- IgG2a
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- 应用备注
- Optimal working dilution should be determined by the investigator.
- 限制
- 仅限研究用
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- 缓冲液
- In 1x PBS, pH 7.4
- 注意事项
- Aliquot to avoid repeated freezing and thawing.
- 储存条件
- -20 °C
- 储存方法
- Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Early preimplantation cells expressing Cdx2 exhibit plasticity of specification to TE and ICM lineages through positional changes." in: Developmental biology, Vol. 411, Issue 1, pp. 50-60, (2016) (PubMed).
: "Multiple Mechanisms Cooperate to Constitutively Exclude the Transcriptional Co-Activator YAP from the Nucleus During Murine Oogenesis." in: Biology of reproduction, Vol. 94, Issue 5, pp. 102, (2016) (PubMed).
: "Toxin A of the nosocomial pathogen Clostridium difficile induces primary effects in the proteome of HEp-2 cells." in: Proteomics. Clinical applications, Vol. 11, Issue 3-4, (2016) (PubMed).
: "Oncoprotein YAP regulates the spindle checkpoint activation in a mitotic phosphorylation-dependent manner through up-regulation of BubR1." in: The Journal of biological chemistry, Vol. 290, Issue 10, pp. 6191-202, (2015) (PubMed).
: "A functional interaction between Hippo-YAP signalling and FoxO1 mediates the oxidative stress response." in: Nature communications, Vol. 5, pp. 3315, (2014) (PubMed).
: "Amot130 adapts atrophin-1 interacting protein 4 to inhibit yes-associated protein signaling and cell growth." in: The Journal of biological chemistry, Vol. 288, Issue 21, pp. 15181-93, (2013) (PubMed).
: "Stromal-epithelial crosstalk regulates kidney progenitor cell differentiation." in: Nature cell biology, Vol. 15, Issue 9, pp. 1035-44, (2013) (PubMed).
: "CDK1 phosphorylation of YAP promotes mitotic defects and cell motility and is essential for neoplastic transformation." in: Cancer research, Vol. 73, Issue 22, pp. 6722-33, (2013) (PubMed).
: "Serum deprivation inhibits the transcriptional co-activator YAP and cell growth via phosphorylation of the 130-kDa isoform of Angiomotin by the LATS1/2 protein kinases." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 110, Issue 43, pp. 17368-73, (2013) (PubMed).
: "YAP1 recruits c-Abl to protect angiomotin-like 1 from Nedd4-mediated degradation." in: PLoS ONE, Vol. 7, Issue 4, pp. e35735, (2012) (PubMed).
: "Tead4 is constitutively nuclear, while nuclear vs. cytoplasmic Yap distribution is regulated in preimplantation mouse embryos." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 109, Issue 50, pp. E3389-90; author reply E3391-2, (2012) (PubMed).
: "LATS2 is a tumor suppressor gene of malignant mesothelioma." in: Cancer research, Vol. 71, Issue 3, pp. 873-83, (2011) (PubMed).
: "Identification of miR-193b targets in breast cancer cells and systems biological analysis of their functional impact." in: Molecular & cellular proteomics : MCP, Vol. 10, Issue 7, pp. M110.005322, (2011) (PubMed).
: "Inactivation of Merlin in malignant mesothelioma cells and the Hippo signaling cascade dysregulation." in: Pathology international, Vol. 61, Issue 6, pp. 331-44, (2011) (PubMed).
: "Hippo pathway regulation by cell morphology and stress fibers." in: Development (Cambridge, England), Vol. 138, Issue 18, pp. 3907-14, (2011) (PubMed).
: "JNK phosphorylates Yes-associated protein (YAP) to regulate apoptosis." in: Cell death & disease, Vol. 1, pp. e29, (2011) (PubMed).
: "Merlin is a potent inhibitor of glioma growth." in: Cancer research, Vol. 68, Issue 14, pp. 5733-42, (2008) (PubMed).
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Early preimplantation cells expressing Cdx2 exhibit plasticity of specification to TE and ICM lineages through positional changes." in: Developmental biology, Vol. 411, Issue 1, pp. 50-60, (2016) (PubMed).
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- 抗原
- YAP1 (Yes-Associated Protein 1 (YAP1))
- 别名
- YAP1 (YAP1 产品)
- 背景
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Full Gene Name: Yes-associated protein 1, 65 kDa
Synonyms: YAP,YAP2,YAP65,YKI - 基因ID
- 10413
- NCBI登录号
- NM_006106
- 途径
- MAPK Pathway, Stem Cell Maintenance, Regulation of Lipid Metabolism by PPARalpha
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