MFN2 抗体 (AA 661-757)
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- 抗原 See all MFN2 抗体
- MFN2 (Mitofusin 2 (MFN2))
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抗原表位
- AA 661-757
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适用
- 人
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This MFN2 antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), RNA Interference (RNAi)
- 原理
- Mouse monoclonal antibody raised against a partial recombinant MFN2.
- 序列
- FKRQFVEHAS EKLQLVISYT GSNCSHQVQQ ELSGTFAHLC QQVDVTRENL EQEIAAMNKK IEVLDSLQSK AKLLRNKAGW LDSELNMFTH QYLQPSR
- 交叉反应
- 人, 大鼠
- 产品特性
- Antibody Reactive Against Recombinant Protein.
- 免疫原
- MFN2 (NP_055689, 661 a.a. ~ 757 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
- 克隆位点
- 4H8
- 亚型
- IgG2a
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- 应用备注
- Optimal working dilution should be determined by the investigator.
- 限制
- 仅限研究用
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- 缓冲液
- In 1x PBS, pH 7.4
- 注意事项
- Aliquot to avoid repeated freezing and thawing.
- 储存条件
- -20 °C
- 储存方法
- Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Mitophagy receptor FUNDC1 regulates mitochondrial dynamics and mitophagy." in: Autophagy, Vol. 12, Issue 4, pp. 689-702, (2016) (PubMed).
: "The Upshot of LRRK2 Inhibition to Parkinson's Disease Paradigm." in: Molecular neurobiology, (2015) (PubMed).
: "Exercise training can induce cardiac autophagy at end-stage chronic conditions: insights from a graft-versus-host-disease mouse model." in: Brain, behavior, and immunity, Vol. 39, pp. 56-60, (2014) (PubMed).
: "Over-expressing mitofusin-2 in healthy mature mammalian skeletal muscle does not alter mitochondrial bioenergetics." in: PLoS ONE, Vol. 8, Issue 1, pp. e55660, (2013) (PubMed).
: "Regulation of miRNAs in human skeletal muscle following acute endurance exercise and short-term endurance training." in: The Journal of physiology, Vol. 591, Issue Pt 18, pp. 4637-53, (2013) (PubMed).
: "Mitofusin-2 independent juxtaposition of endoplasmic reticulum and mitochondria: an ultrastructural study." in: PLoS ONE, Vol. 7, Issue 9, pp. e46293, (2012) (PubMed).
: "Mitochondrial bioenergetics and dynamics interplay in complex I-deficient fibroblasts." in: Biochimica et biophysica acta, Vol. 1802, Issue 5, pp. 443-53, (2010) (PubMed).
: "PGC-1alpha's relationship with skeletal muscle palmitate oxidation is not present with obesity despite maintained PGC-1alpha and PGC-1beta protein." in: American journal of physiology. Endocrinology and metabolism, Vol. 294, Issue 6, pp. E1060-9, (2008) (PubMed).
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Mitophagy receptor FUNDC1 regulates mitochondrial dynamics and mitophagy." in: Autophagy, Vol. 12, Issue 4, pp. 689-702, (2016) (PubMed).
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- 抗原
- MFN2 (Mitofusin 2 (MFN2))
- 别名
- MFN2 (MFN2 产品)
- 背景
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Full Gene Name: mitofusin 2
Synonyms: CMT2A,CMT2A2,CPRP1,HSG,KIAA0214,MARF - 基因ID
- 9927
- NCBI登录号
- NM_014874
- 途径
- Skeletal Muscle Fiber Development
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