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USP9X 抗体 (AA 1-90)

USP9X 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 1C4 unconjugated
产品编号 ABIN563570
发货至: 中国
  • 抗原 See all USP9X 抗体
    USP9X (Ubiquitin Specific Peptidase 9, X-Linked (USP9X))
    抗原表位
    • 10
    • 5
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1-90
    适用
    • 54
    • 34
    • 30
    • 6
    • 4
    • 4
    • 4
    • 2
    • 2
    • 1
    • 1
    宿主
    • 48
    • 4
    • 2
    小鼠
    克隆类型
    • 42
    • 12
    单克隆
    标记
    • 23
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This USP9X antibody is un-conjugated
    应用范围
    • 33
    • 14
    • 9
    • 8
    • 7
    • 6
    • 4
    • 2
    • 2
    • 1
    Western Blotting (WB), ELISA, Immunofluorescence (IF)
    原理
    Mouse monoclonal antibody raised against a partial recombinant USP9X.
    序列
    MTATTRGSPV GGNDNQGQAP DGQSQPPLQQ NQTSSPDSSN ENSPATPPDE QGQGDAPPQL EDEEPAFPHT DLAKLDDMIN RPRWVVPVLP
    交叉反应
    产品特性
    Antibody Reactive Against Recombinant Protein.
    免疫原
    USP9X (NP_068706, 1 a.a. ~ 90 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
    克隆位点
    1C4
    亚型
    IgG1
    Top Product
    Discover our top product USP9X Primary Antibody
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 缓冲液
    In 1x PBS, pH 7.4
    注意事项
    Aliquot to avoid repeated freezing and thawing.
    储存条件
    -20 °C
    储存方法
    Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
  • Kim, Kim, Park, Lee, Lim: "Role of Angiomotin-like 2 mono-ubiquitination on YAP inhibition." in: EMBO reports, Vol. 17, Issue 1, pp. 64-78, (2016) (PubMed).

    Wolfsperger, Hogh-Binder, Schittenhelm, Psaras, Ritter, Bornes, Huber, Jendrossek, Rudner: "Deubiquitylating enzyme USP9x regulates radiosensitivity in glioblastoma cells by Mcl-1-dependent and -independent mechanisms." in: Cell death & disease, Vol. 7, pp. e2039, (2016) (PubMed).

    Wang, Xie, Li, Owonikoko, Ramalingam, Khuri, Curran, Wang, Deng: "Role of Ku70 in deubiquitination of Mcl-1 and suppression of apoptosis." in: Cell death and differentiation, Vol. 21, Issue 7, pp. 1160-9, (2014) (PubMed).

    Mazumder, Choudhary, Al-Harbi, Almasan: "Mcl-1 Phosphorylation defines ABT-737 resistance that can be overcome by increased NOXA expression in leukemic B cells." in: Cancer research, Vol. 72, Issue 12, pp. 3069-79, (2012) (PubMed).

    Trivigno, Essmann, Huber, Rudner: "Deubiquitinase USP9x confers radioresistance through stabilization of Mcl-1." in: Neoplasia (New York, N.Y.), Vol. 14, Issue 10, pp. 893-904, (2012) (PubMed).

    Hikita, Takehara, Shimizu, Kodama, Shigekawa, Iwase, Hosui, Miyagi, Tatsumi, Ishida, Li, Kanto, Hiramatsu, Hayashi: "The Bcl-xL inhibitor, ABT-737, efficiently induces apoptosis and suppresses growth of hepatoma cells in combination with sorafenib." in: Hepatology (Baltimore, Md.), Vol. 52, Issue 4, pp. 1310-21, (2010) (PubMed).

  • 抗原
    USP9X (Ubiquitin Specific Peptidase 9, X-Linked (USP9X))
    别名
    USP9X (USP9X 产品)
    背景
    Full Gene Name: ubiquitin specific peptidase 9, X-linked
    Synonyms: DFFRX,FAF,FAM
    基因ID
    8239
    NCBI登录号
    NM_021906
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