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CD41, CD61 抗体

Name: CD41, CD61 抗体
Brand: antibodies-online
SKU: ABIN5633262
Availability: OutOfStock

适用: 人 FACS, IP, ICC 宿主: 小鼠 Monoclonal PAC-1 unconjugated

Flow cytometry surface staining pattern of PHA stimulated human peripheral whole blood stained using anti-human CD41/CD61 (PAC-1) purified antibody (concentration in sample 8 μg/mL, GAM PE). (CD41, CD61 抗体)

FACS

Surface staining of PAC-1 on PHA-activated (1 hour) human peripheral blood with anti-PAC-1 (PAC-1) FITC. (CD41, CD61 抗体)

FACS

Separation of CD41/CD61 positive platelets (red-filled) from CD41/CD61 negative nucleated cells (black-dashed) in flow cytometry analysis (surface staining) of PHA stimulated human peripheral whole blood stained using anti-human CD41/CD61 (PAC-1) purified antibody (concentration in sample 8 μg/mL, GAM PE). (CD41, CD61 抗体)

FACS

Flow cytometry multicolor staining pattern of human lymphocytes stained using anti-human CD41/CD61 (PAC-1) purified antibody (concentration in sample 8 μg/mL, GAM PE) and Hoechst 34580. (CD41, CD61 抗体)

FACS

4 images

产品编号 ABIN5633262

发货至: 中国

Datasheet as PDF

抗原 See all CD41, CD61 抗体

CD41, CD61 (CD41,CD61)
适用
12

6

3

1

1

1

1

1

1
人
宿主
20
小鼠
Compatible Secondaries
克隆类型
20
单克隆
标记
9

4

4

2

1
This CD41, CD61 antibody is un-conjugated
应用范围
16

7

5

4

3

2

2

2

1
Flow Cytometry (FACS), Immunoprecipitation (IP), Immunocytochemistry (ICC)

特异性

The mouse monoclonal antibody PAC-1 recognizes an extracellular activation-induced conformational epitope PAC-1 on CD41/CD61 complex (gpIIb/IIIa), also known as integrin alpha IIb beta 3, a receptor which mediates platelet aggregation.

交叉反应（详细）

Human

纯化方法

Purified by sequential steps of physicochemical fractionation (differential precipitation and solid-phase chromatography methods).

纯度

> 95 % (by SDS-PAGE)

免疫原

Human platelets

克隆位点

PAC-1

亚型

IgM kappa

Top Product

Discover our top product CD41, CD61 Primary Antibody
anti-CD41,CD61 antibody
适用: 人, Cow FACS, IP, ELISA, ICC 宿主: 小鼠 Monoclonal IVA30 unconjugated

anti-CD41,CD61 antibody (PE)
适用: 人 FACS 宿主: 小鼠 Monoclonal PAC-1 PE

anti-CD41,CD61 antibody (PerCP)
适用: 人 FACS 宿主: 小鼠 Monoclonal PAC-1 PerCP

anti-CD41,CD61 antibody (FITC)
适用: 人 FACS 宿主: 小鼠 Monoclonal PAC-1 FITC

anti-CD41,CD61 antibody
适用: Cow, 绵羊, Cat, 犬, 山羊, 马, 兔 FACS, IP, ELISA 宿主: 小鼠 Monoclonal CO-35E4 unconjugated

anti-CD41,CD61 antibody (PerCP)
适用: 人 FACS 宿主: 小鼠 Monoclonal PAC-1 PerCP

anti-CD41,CD61 antibody (FITC)
适用: 小鸡 FACS, IP, IF 宿主: 小鼠 Monoclonal FITC

anti-CD41,CD61 antibody (PE)
适用: 小鸡 FACS, IP, IF 宿主: 小鼠 Monoclonal PE

anti-CD41,CD61 antibody (PE)
适用: 小鸡 FACS 宿主: 小鼠 Monoclonal PE

anti-CD41,CD61 antibody
适用: Cow FACS, EIA, IP, IHC (fro) 宿主: 小鼠 Monoclonal IVA30 unconjugated

应用备注

Flow cytometry: Recommended dilution: 2-4 μg/mL.

限制

仅限研究用
浓度

1 mg/mL

缓冲液

Tris buffered saline (TBS), pH 8.0, 15 mM sodium azide

储存液

Sodium azide

注意事项

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

储存条件

4 °C

储存方法

Store at 2-8°C. Do not freeze.
抗原

CD41, CD61 (CD41,CD61)

别名

CD41/CD61 (CD41, CD61 产品)

背景

CD41 (platelet glycoprotein IIb, integrin alpha IIb) is composed of two subunits (120 kDa transmembrane alpha chain and 23 kDa extracellular beta chain) and interacts with CD61 (platelet glycoprotein IIIa, integrin beta 3) in the presence of calcium to form a functional adhesive protein receptor. CD41/CD61 complex is one of the earliest markers of the megakaryocytic lineage. Upon blood vessel damage, this receptor binds to a variety of proteins including von Willebrand factor, fibrinogen, fibronectin and vitronectin, and it is involved in platelet aggregation.,platelet GPIIb, Integrin alpha-Iib, GPalpha IIb, GPIIb, GT, GP3A, platelet GPIIIa