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RRM2 抗体 (AA 1-110)

RRM2 适用: 人 WB, ELISA, IF, IP, IHC (p) 宿主: 小鼠 Monoclonal 1E1 unconjugated
产品编号 ABIN562744
发货至: 中国
  • 抗原 See all RRM2 抗体
    RRM2 (Ribonucleotide Reductase M2 (RRM2))
    抗原表位
    • 15
    • 8
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1-110
    适用
    • 57
    • 14
    • 13
    • 2
    • 2
    • 1
    • 1
    • 1
    宿主
    • 52
    • 5
    小鼠
    克隆类型
    • 43
    • 13
    • 1
    单克隆
    标记
    • 25
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This RRM2 antibody is un-conjugated
    应用范围
    • 39
    • 15
    • 13
    • 13
    • 10
    • 7
    • 6
    • 5
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunoprecipitation (IP), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    原理
    Mouse monoclonal antibody raised against a partial recombinant RRM2.
    序列
    MLSLRVPLAP ITDPQQLQLS PLKGLSLVDK ENTPPALSGT RVLASKTARR IFQEPTEPKT KAAAPGVEDE PLLRENPRRF VIFPIEYHDI WQMYKKAEAS FWTAEEVDLS
    交叉反应
    产品特性
    Antibody Reactive Against Recombinant Protein.
    免疫原
    RRM2 (NP_001025, 1 a.a. ~ 110 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
    克隆位点
    1E1
    亚型
    IgG1
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 缓冲液
    In 1x PBS, pH 7.4
    注意事项
    Aliquot to avoid repeated freezing and thawing.
    储存条件
    -20 °C
    储存方法
    Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
  • Castelblanco, Zafon, Maravall, Gallel, Martinez, Capel, Bella, Halperin, Temprana, Iglesias, Puig-Domingo, Robledo, Matias-Guiu, Mauricio: "APLP2, RRM2, and PRC1: New Putative Markers for the Differential Diagnosis of Thyroid Follicular Lesions." in: Thyroid : official journal of the American Thyroid Association, Vol. 27, Issue 1, pp. 59-66, (2016) (PubMed).

    Kim, Park, Joo, Shen, Hong, Kim, Singh, Lee, Shin: "RRM1 maintains centrosomal integrity via CHK1 and CDK1 signaling during replication stress." in: Cancer letters, Vol. 346, Issue 2, pp. 249-56, (2014) (PubMed).

    Yoshida, Tsunoda, Doi, Tanaka, Fujimoto, Machida, Ota, Koyanagi, Takashima, Sasazuki, Kuroki, Iwasaki, Shirasawa: "KRAS-mediated up-regulation of RRM2 expression is essential for the proliferation of colorectal cancer cell lines." in: Anticancer research, Vol. 31, Issue 7, pp. 2535-9, (2011) (PubMed).

    Zhou, Snyder, Lieberman: "Epstein-Barr virus episome stability is coupled to a delay in replication timing." in: Journal of virology, Vol. 83, Issue 5, pp. 2154-62, (2009) (PubMed).

    Tang, Deng, Wang, Dai, Wang, Jiang, Li, Li, Sheng, Wu, Li, Zeng et al.: "Quantitative phosphoproteome profiling of Wnt3a-mediated signaling network: indicating the involvement of ribonucleoside-diphosphate reductase M2 subunit phosphorylation at residue serine 20 in ..." in: Molecular & cellular proteomics : MCP, Vol. 6, Issue 11, pp. 1952-67, (2007) (PubMed).

  • 抗原
    RRM2 (Ribonucleotide Reductase M2 (RRM2))
    别名
    RRM2 (RRM2 产品)
    背景
    Full Gene Name: ribonucleotide reductase M2 polypeptide
    Synonyms: R2,RR2M
    基因ID
    6241
    NCBI登录号
    NM_001034
    途径
    Mitotic G1-G1/S Phases
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