NOTCH3 抗体 (AA 47-156)
-
- 抗原 See all NOTCH3 抗体
- NOTCH3 (Notch 3 (NOTCH3))
-
抗原表位
- AA 47-156
-
适用
- 人
-
宿主
- 小鼠
-
克隆类型
- 单克隆
-
标记
- This NOTCH3 antibody is un-conjugated
-
应用范围
- Western Blotting (WB), ELISA
- 原理
- Mouse monoclonal antibody raised against a partial recombinant NOTCH3.
- 序列
- SPCANGGRCT QLPSREAACL CPPGWVGERC QLEDPCHSGP CAGRGVCQSS VVAGTARFSC RCPRGFRGPD CSLPDPCLSS PCAHGARCSV GPDGRFLCSC PPGYQGRSCR
- 交叉反应
- 人
- 产品特性
- Antibody Reactive Against Recombinant Protein.
- 免疫原
- NOTCH3 (NP_000426, 47 a.a. ~ 156 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
- 克隆位点
- 1G5
- 亚型
- IgG2a
- Top Product
- Discover our top product NOTCH3 Primary Antibody
-
-
- 应用备注
- Optimal working dilution should be determined by the investigator.
- 限制
- 仅限研究用
-
- 缓冲液
- In 1x PBS, pH 7.4
- 注意事项
- Aliquot to avoid repeated freezing and thawing.
- 储存条件
- -20 °C
- 储存方法
- Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
-
-
Von Willebrand factor inhibits mature smooth muscle gene expression through impairment of Notch signaling." in: PLoS ONE, Vol. 8, Issue 9, pp. e75808, (2013) (PubMed).
: "Transendocytosis is impaired in CADASIL-mutant NOTCH3." in: Experimental neurology, Vol. 233, Issue 1, pp. 303-11, (2012) (PubMed).
: "Functional analysis of the Notch ligand Jagged1 missense mutant proteins underlying Alagille syndrome." in: The FEBS journal, Vol. 279, Issue 12, pp. 2096-107, (2012) (PubMed).
: "Bidirectional encroachment of collagen into the tunica media in cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy." in: Brain research, Vol. 1456, pp. 64-71, (2012) (PubMed).
: "Cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy affecting an African American man: identification of a novel 15-base pair NOTCH3 duplication." in: Archives of neurology, Vol. 68, Issue 12, pp. 1584-6, (2011) (PubMed).
: "Thrombospondin 2 potentiates notch3/jagged1 signaling." in: The Journal of biological chemistry, Vol. 284, Issue 12, pp. 7866-74, (2009) (PubMed).
: "Identification of Pbx1, a potential oncogene, as a Notch3 target gene in ovarian cancer." in: Cancer research, Vol. 68, Issue 21, pp. 8852-60, (2008) (PubMed).
: "
-
Von Willebrand factor inhibits mature smooth muscle gene expression through impairment of Notch signaling." in: PLoS ONE, Vol. 8, Issue 9, pp. e75808, (2013) (PubMed).
-
- 抗原
- NOTCH3 (Notch 3 (NOTCH3))
- 别名
- NOTCH3 (NOTCH3 产品)
- 背景
-
Full Gene Name: Notch homolog 3 (Drosophila)
Synonyms: CADASIL,CASIL - 基因ID
- 4854
- NCBI登录号
- NM_000435
- 途径
- Notch Signaling
-