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K-RAS 抗体 (AA 1-188)

KRAS 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 3B10-2F2 unconjugated
产品编号 ABIN561621
发货至: 中国
  • 抗原 See all K-RAS (KRAS) 抗体
    K-RAS (KRAS) (GTPase Kras (KRAS))
    抗原表位
    • 16
    • 11
    • 8
    • 6
    • 6
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1-188
    适用
    • 59
    • 39
    • 32
    • 5
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    宿主
    • 63
    • 9
    小鼠
    克隆类型
    • 63
    • 9
    单克隆
    标记
    • 29
    • 7
    • 4
    • 4
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This K-RAS antibody is un-conjugated
    应用范围
    • 62
    • 28
    • 23
    • 13
    • 13
    • 12
    • 10
    • 6
    • 5
    • 4
    • 3
    • 1
    Western Blotting (WB), ELISA, Immunofluorescence (IF)
    原理
    Mouse monoclonal antibody raised against a full length recombinant KRAS.
    序列
    MTEYKLVVVG AGGVGKSALT IQLIQNHFVD EYDPTIEDSY RKQVVIDGET CLLDILDTAG HEEYSAMRDQ YMRTGEGFLC VFAINNTKSF EDIHHYREQI KRVKDSEDVP MVLVGNKCDL PSRTVDTKQA QDLARSYGIP FIETSAKTRQ GVDDAFYTLV REIRKHKEKM SKDGKKKKKK SKTKCVIM
    交叉反应
    产品特性
    Antibody Reactive Against Recombinant Protein.
    免疫原
    KRAS (AAH13572, 1 a.a. ~ 188 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
    克隆位点
    3B10-2F2
    亚型
    IgG1
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 缓冲液
    In 1x PBS, pH 7.4
    注意事项
    Aliquot to avoid repeated freezing and thawing.
    储存条件
    -20 °C
    储存方法
    Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
  • Madureira, Bharadwaj, Bydoun, Garant, OConnell, Lee, Waisman: "Cell surface protease activation during RAS transformation: Critical role of the plasminogen receptor, S100A10." in: Oncotarget, Vol. 7, Issue 30, pp. 47720-47737, (2016) (PubMed).

    King, Bray, Galbraith, Christie, Fleming: "Evidence for aldosterone-dependent growth of renal cell carcinoma." in: International journal of experimental pathology, Vol. 95, Issue 4, pp. 244-50, (2014) (PubMed).

    Ambrosini, Khanin, Carvajal, Schwartz: "Overexpression of DDX43 mediates MEK inhibitor resistance through RAS Upregulation in uveal melanoma cells." in: Molecular cancer therapeutics, Vol. 13, Issue 8, pp. 2073-80, (2014) (PubMed).

    Valtorta, Misale, Sartore-Bianchi, Nagtegaal, Paraf, Lauricella, Dimartino, Hobor, Jacobs, Ercolani, Lamba, Scala, Veronese, Laurent-Puig, Siena, Tejpar, Mottolese, Punt, Gambacorta, Bardelli et al.: "KRAS gene amplification in colorectal cancer and impact on response to EGFR-targeted therapy. ..." in: International journal of cancer. Journal international du cancer, Vol. 133, Issue 5, pp. 1259-65, (2013) (PubMed).

    Fuentes-Calvo, Blázquez-Medela, Santos, López-Novoa, Martínez-Salgado: "Analysis of k-ras nuclear expression in fibroblasts and mesangial cells." in: PLoS ONE, Vol. 5, Issue 1, pp. e8703, (2010) (PubMed).

  • 抗原
    K-RAS (KRAS) (GTPase Kras (KRAS))
    别名
    KRAS (KRAS 产品)
    物质类
    Viral Protein
    背景
    Full Gene Name: v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog
    Synonyms: C-K-RAS,K-RAS2A,K-RAS2B,K-RAS4A,K-RAS4B,KI-RAS,KRAS1,KRAS2,NS3,RASK2
    基因ID
    3845
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