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HMGB1 抗体 (AA 1-215)

Name: HMGB1 抗体 (AA 1-215)
SKU: ABIN561281
Availability: OutOfStock

HMGB1 适用: 人 WB, ELISA, IF, IHC (p) 宿主: 小鼠 Monoclonal 1D5 unconjugated

Western Blot analysis of HMGB1 expression in transfected 293T cell line by HMGB1 monoclonal antibody (M02), clone 1D5. (HMGB1 抗体 (AA 1-215))

Western Blot detection against Immunogen (49. (HMGB1 抗体 (AA 1-215))

Immunoperoxidase of monoclonal antibody to HMGB1 on formalin-fixed paraffin-embedded human hepatocellular carcinoma tissue. (HMGB1 抗体 (AA 1-215))

ISt

Immunofluorescence of monoclonal antibody to HMGB1 on HeLa cell. (HMGB1 抗体 (AA 1-215))

HMGB1 monoclonal antibody (M02), clone 1D5 Western Blot analysis of HMGB1 expression in K-562 . (HMGB1 抗体 (AA 1-215))

5 images

(5 references)

产品编号 ABIN561281

发货至: 中国

Datasheet as PDF

抗原 See all HMGB1 抗体

HMGB1 (High Mobility Group Box 1 (HMGB1))
抗原表位
21

16

16

10

10

8

6

6

6

4

4

3

3

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
AA 1-215
适用
154

92

91

13

11

11

10

8

6

6

6

6

5

2

1

1

1
人
宿主
135

29

2

2

1

1
小鼠
Compatible Secondaries
克隆类型
128

42
单克隆
标记
82

17

17

7

6

6

2

2

2

2

2

2

2

2

2

2

2

2

2

2

2

2

2

1
This HMGB1 antibody is un-conjugated
应用范围
137

61

45

45

31

28

27

26

20

10

9

5

2

2

1

1

1

1

1

1
Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

原理

Mouse monoclonal antibody raised against a full length recombinant HMGB1.

序列

MGKGDPKKPR GKMSSYAFFV QTCREEHKKK HPDASVNFSE FSKKCSERWK TMSAKEKGKF EDMAKADKAR YEREMKTYIP PKGETKKKFK DPNAPKRPPS AFFLFCSEYR PKIKGEHPGL SIGDVAKKLG EMWNNTAADD KQPYEKKAAK LKEKYEKDIA AYRAKGKPDA AKKGVVKAEK SKKKKEEEED EEDEEDEEEE EDEEDEDEEE DDDDE

交叉反应

人

产品特性

Antibody Reactive Against Recombinant Protein.

免疫原

HMGB1 (AAH03378.1, 1 a.a. ~ 215 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

克隆位点

1D5

亚型

IgG2a

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anti-High Mobility Group Box 1 (HMGB1) antibody
KO Validated HMGB1 适用: 人 WB, IHC, IF, IHC (p), ICC, IHC (wm), IHC (ff) 宿主: 兔 Polyclonal unconjugated

anti-High Mobility Group Box 1 (HMGB1) (AA 9-163) antibody
HMGB1 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated

anti-High Mobility Group Box 1 (HMGB1) (AA 1-215) antibody
HMGB1 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated

anti-High Mobility Group Box 1 (HMGB1) (AA 1-215) antibody
HMGB1 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated

anti-High Mobility Group Box 1 (HMGB1) (AA 1-215) antibody
HMGB1 适用: 人 WB, ELISA, IF, IHC (p) 宿主: 小鼠 Monoclonal 1E6-E10 unconjugated

anti-High Mobility Group Box 1 (HMGB1) (AA 124-154), (C-Term) antibody
HMGB1 适用: 人, 小鼠, 大鼠 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated

anti-High Mobility Group Box 1 (HMGB1) (AA 1-215) antibody
HMGB1 适用: 人 WB, IHC, IP, ICC 宿主: 小鼠 Monoclonal 1# unconjugated

anti-High Mobility Group Box 1 (HMGB1) (N-Term) antibody
HMGB1 适用: 人, 小鼠, 大鼠 WB, ELISA, IF, IHC (p) 宿主: 兔 Polyclonal unconjugated

应用备注

Optimal working dilution should be determined by the investigator.

限制

仅限研究用
缓冲液

In 1x PBS, pH 7.4

注意事项

Aliquot to avoid repeated freezing and thawing.

储存条件

-20 °C

储存方法

Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
Ko, Hsu, Hsieh, Lien, Lee, Kou: "High expression of high-mobility group box 1 in the blood and lungs is associated with the development of chronic obstructive pulmonary disease in smokers." in: Respirology (Carlton, Vic.), Vol. 19, Issue 2, pp. 253-61, (2014) (PubMed).

Demoulin, Herfs, Somja, Roncarati, Delvenne, Hubert: "HMGB1 secretion during cervical carcinogenesis promotes the acquisition of a tolerogenic functionality by plasmacytoid dendritic cells." in: International journal of cancer. Journal international du cancer, (2014) (PubMed).

Hirano, Yoshioka, Yunoue, Fujio, Yonezawa, Niiro, Habu, Oyoshi, Sugata, Kamezawa, Arimura, Hanaya, Tokimura, Tokudome, Arita: "TLR4, IL-6, IL-18, MyD88 and HMGB1 are highly expressed in intracranial inflammatory lesions and the IgG4/IgG ratio correlates with TLR4 and IL-6." in: Neuropathology : official journal of the Japanese Society of Neuropathology, Vol. 32, Issue 6, pp. 628-37, (2012) (PubMed).

Krüger, Krick, Dhillon, Lerner, Ames, Bromberg, Lin, Walsh, Vella, Fischereder, Krämer, Colvin, Heeger, Murphy, Schröppel: "Donor Toll-like receptor 4 contributes to ischemia and reperfusion injury following human kidney transplantation." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 106, Issue 9, pp. 3390-5, (2009) (PubMed).

Kijanka, Hector, Kay, Murray, Cummins, Murphy, MacCraith, Prehn, Kenny: "Human IgG antibody profiles differentiate between symptomatic patients with and without colorectal cancer." in: Gut, Vol. 59, Issue 1, pp. 69-78, (2009) (PubMed).
抗原

HMGB1 (High Mobility Group Box 1 (HMGB1))

别名

HMGB1 (HMGB1 产品)

别名

HMG1 antibody, HMG3 antibody, SBP-1 antibody, DEF antibody, HMG-1 antibody, Hmg1 antibody, amphoterin antibody, p30 antibody, hmgb1 antibody, ik:tdsubc_1a5 antibody, wu:fb23c02 antibody, xx:tdsubc_1a5 antibody, zgc:56110 antibody, zgc:77104 antibody, hmg-1 antibody, hmg3 antibody, sbp-1 antibody, hmg1 antibody, HMGB1 antibody, Ac2-008 antibody, high mobility group box 1 antibody, high-mobility group box 1 antibody, high mobility group box 1a antibody, high mobility group box 1 L homeolog antibody, high mobility group protein B1 antibody, HMGB1 antibody, Hmgb1 antibody, hmgb1 antibody, hmgb1a antibody, hmgb1.L antibody, LOC100359149 antibody

背景

Full Gene Name: high-mobility group box 1
Synonyms: DKFZp686A04236,HMG1,HMG3,SBP-1

基因ID

3146

途径

p53 Pathway, Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development, Positive Regulation of Endopeptidase Activity, Regulation of Carbohydrate Metabolic Process, Toll-Like Receptors Cascades, Smooth Muscle Cell Migration, Inflammasome