DDR1 抗体 (AA 21-176)
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- 抗原 See all DDR1 抗体
- DDR1 (Discoidin Domain Receptor tyrosine Kinase 1 (DDR1))
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抗原表位
- AA 21-176
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适用
- 人
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This DDR1 antibody is un-conjugated
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应用范围
- ELISA, Flow Cytometry (FACS)
- 原理
- CD167 Antibody
- 纯化方法
- Purified antibody
- 免疫原
- Purified recombinant fragment of human CD167 (AA: 21-176) expressed in E. Coli.
- 克隆位点
- 4F2C12
- 亚型
- IgG2b
- Top Product
- Discover our top product DDR1 Primary Antibody
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- 应用备注
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ELISA: 1/10000
FCM: 1/200 - 1/400
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- Purified antibody in PBS with 0.05 % sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
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- 抗原
- DDR1 (Discoidin Domain Receptor tyrosine Kinase 1 (DDR1))
- 别名
- CD167 (DDR1 产品)
- 背景
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Description: Receptor tyrosine kinases play a key role in the communication of cells with their microenvironment. These kinases are involved in the regulation of cell growth, differentiation and metabolism. The protein encoded by this gene belongs to a subfamily of tyrosine kinase receptors with homology to Dictyostelium discoideum protein discoidin I in their extracellular domain, and that are activated by various types of collagen. Expression of this protein is restricted to epithelial cells, particularly in the kidney, lung, gastrointestinal tract, and brain. In addition, it has been shown to be significantly overexpressed in several human tumors. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.
Aliases: DDR1,CAK, DDR, NEP, HGK2, PTK3, RTK6, TRKE, EDDR1, MCK10, NTRK4, PTK3A
- 分子量
- 101kDa
- 基因ID
- 780
- HGNC
- 780
- UniProt
- Q08345
- 途径
- RTK signaling, Smooth Muscle Cell Migration
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