CCR1 抗体
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- 抗原 See all CCR1 抗体
- CCR1 (Chemokine (C-C Motif) Receptor 1 (CCR1))
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适用
- 人
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This CCR1 antibody is un-conjugated
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应用范围
- ELISA, Flow Cytometry (FACS)
- 原理
- CD191 Antibody
- 纯化方法
- Purified antibody
- 免疫原
- Purified recombinant fragment of human CD191 (AA: mix) expressed in E. Coli.
- 克隆位点
- 8E10G6
- 亚型
- IgG1
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- 应用备注
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ELISA: 1/10000
FCM: 1/200 - 1/400
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- Purified antibody in PBS with 0.05 % sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
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- 抗原
- CCR1 (Chemokine (C-C Motif) Receptor 1 (CCR1))
- 别名
- CD191 (CCR1 产品)
- 别名
- CD191 antibody, CKR-1 antibody, CKR1 antibody, CMKBR1 antibody, HM145 antibody, MIP1aR antibody, SCYAR1 antibody, Cmkbr1 antibody, Mip-1a-R antibody, C-C motif chemokine receptor 1 antibody, chemokine (C-C motif) receptor 1 antibody, CCR1 antibody, Ccr1 antibody
- 背景
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Description: This gene encodes a member of the beta chemokine receptor family, which is predicted to be a seven transmembrane protein similar to G protein-coupled receptors. The ligands of this receptor include macrophage inflammatory protein 1 alpha (MIP-1 alpha), regulated on activation normal T expressed and secreted protein (RANTES), monocyte chemoattractant protein 3 (MCP-3), and myeloid progenitor inhibitory factor-1 (MPIF-1). Chemokines and their receptors mediated signal transduction are critical for the recruitment of effector immune cells to the site of inflammation. Knockout studies of the mouse homolog suggested the roles of this gene in host protection from inflammatory response, and susceptibility to virus and parasite. This gene and other chemokine receptor genes, including CCR2, CCRL2, CCR3, CCR5 and CCXCR1, are found to form a gene cluster on chromosome 3p.
Aliases: CCR1, CKR1, CKR-1, HM145, CMKBR1, MIP1aR, SCYAR1
- 分子量
- 41.2kDa
- 基因ID
- 1230
- HGNC
- 1230
- UniProt
- P32246
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