CCR5 抗体
-
- 抗原 See all CCR5 抗体
- CCR5 (Chemokine (C-C Motif) Receptor 5 (CCR5))
-
适用
- 人
-
宿主
- 小鼠
-
克隆类型
- 单克隆
-
标记
- This CCR5 antibody is un-conjugated
-
应用范围
- Western Blotting (WB), ELISA, Flow Cytometry (FACS)
- 原理
- CD195 Antibody
- 纯化方法
- Purified antibody
- 免疫原
- Purified recombinant fragment of human CD195 (AA: mix) expressed in E. Coli.
- 克隆位点
- 6H3D5
- 亚型
- IgG1
- Top Product
- Discover our top product CCR5 Primary Antibody
-
-
- 应用备注
-
ELISA: 1/10000
FCM: 1/200 - 1/400
- 限制
- 仅限研究用
-
- 状态
- Liquid
- 缓冲液
- Purified antibody in PBS with 0.05 % sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
-
- 抗原
- CCR5 (Chemokine (C-C Motif) Receptor 5 (CCR5))
- 别名
- CD195 (CCR5 产品)
- 别名
- CC-CKR-5 antibody, CCCKR5 antibody, CCR-5 antibody, CD195 antibody, CKR-5 antibody, CKR5 antibody, CMKBR5 antibody, IDDM22 antibody, Ckr5 antibody, Cmkbr5 antibody, CCR1-L antibody, GPCR antibody, CCR5 antibody, AM4-7 antibody, C-C motif chemokine receptor 5 (gene/pseudogene) antibody, chemokine (C-C motif) receptor 5 antibody, C-C motif chemokine receptor 5 antibody, CCR5 antibody, Ccr5 antibody
- 背景
-
Description: This gene encodes a member of the beta chemokine receptor family, which is predicted to be a seven transmembrane protein similar to G protein-coupled receptors. This protein is expressed by T cells and macrophages, and is known to be an important co-receptor for macrophage-tropic virus, including HIV, to enter host cells. Defective alleles of this gene have been associated with the HIV infection resistance. The ligands of this receptor include monocyte chemoattractant protein 2 (MCP-2), macrophage inflammatory protein 1 alpha (MIP-1 alpha), macrophage inflammatory protein 1 beta (MIP-1 beta) and regulated on activation normal T expressed and secreted protein (RANTES). Expression of this gene was also detected in a promyeloblastic cell line, suggesting that this protein may play a role in granulocyte lineage proliferation and differentiation. This gene is located at the chemokine receptor gene cluster region. An allelic polymorphism in this gene results in both functional and non-functional alleles, the reference genome represents the functional allele. Two transcript variants encoding the same protein have been found for this gene.
Aliases: CCR5, CKR5, CCR-5, CKR-5, CCCKR5, CMKBR5, IDDM22, CC-CKR-5
- 分子量
- 40.5kDa
- 基因ID
- 1234
- HGNC
- 1234
- UniProt
- P51681
- 途径
- Cellular Response to Molecule of Bacterial Origin, cAMP Metabolic Process, Regulation of Cell Size
-