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Axin 抗体 (AA 546-752)

AXIN1 适用: 人 ELISA, ICC, FACS 宿主: 小鼠 Monoclonal 4E9F1 unconjugated
产品编号 ABIN5611198
发货至: 中国
  • 抗原 See all Axin (AXIN1) 抗体
    Axin (AXIN1) (Axin 1 (AXIN1))
    抗原表位
    • 15
    • 15
    • 15
    • 13
    • 8
    • 8
    • 7
    • 6
    • 6
    • 6
    • 5
    • 5
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 546-752
    适用
    • 80
    • 59
    • 32
    • 1
    • 1
    宿主
    • 107
    • 5
    • 1
    小鼠
    克隆类型
    • 108
    • 5
    单克隆
    标记
    • 33
    • 10
    • 9
    • 8
    • 5
    • 5
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This Axin antibody is un-conjugated
    应用范围
    • 84
    • 46
    • 39
    • 39
    • 23
    • 11
    • 9
    • 6
    • 5
    • 4
    • 2
    • 1
    ELISA, Immunocytochemistry (ICC), Flow Cytometry (FACS)
    原理
    AXIN1 Antibody
    纯化方法
    Purified antibody
    免疫原
    Purified recombinant fragment of human AXIN1 (AA: 546-752) expressed in E. Coli.
    克隆位点
    4E9F1
    亚型
    IgG2b
  • 应用备注

    ELISA: 1/10000

    FCM: 1/200 - 1/400

    ICC: 1/50 - 1/250

    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Purified antibody in PBS with 0.05 % sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
  • 抗原
    Axin (AXIN1) (Axin 1 (AXIN1))
    别名
    AXIN1 (AXIN1 产品)
    别名
    AXIN1 antibody, axin antibody, fused antibody, xAxin antibody, LOC100226467 antibody, AXIN antibody, PPP1R49 antibody, AI316800 antibody, Axin antibody, Fu antibody, Kb antibody, Ki antibody, kinky antibody, knobbly antibody, AXIN1-RGS antibody, wu:fi22e03 antibody, wu:fj14c08 antibody, wu:fk11b03 antibody, zgc:109872 antibody, axin 1 antibody, axin 1 S homeolog antibody, axin 1 L homeolog antibody, AXIN1 antibody, axin1.S antibody, axin1.L antibody, Axin1 antibody, axin1 antibody
    背景

    Description: This gene encodes a cytoplasmic protein which contains a regulation of G-protein signaling (RGS) domain and a dishevelled and axin (DIX) domain. The encoded protein interacts with adenomatosis polyposis coli, catenin beta-1, glycogen synthase kinase 3 beta, protein phosphate 2, and itself. This protein functions as a negative regulator of the wingless-type MMTV integration site family, member 1 (WNT) signaling pathway and can induce apoptosis. The crystal structure of a portion of this protein, alone and in a complex with other proteins, has been resolved. Mutations in this gene have been associated with hepatocellular carcinoma, hepatoblastomas, ovarian endometriod adenocarcinomas, and medullablastomas. Alternative splicing results in multiple transcript variants.

    Aliases: AXIN, PPP1R49

    分子量
    95.6kDa
    基因ID
    8312
    HGNC
    8312
    UniProt
    O15169
    途径
    WNT signaling, Sensory Perception of Sound, Regulation of G-Protein Coupled Receptor Protein Signaling
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