Metabotropic Glutamate Receptor 5 抗体 (AA 458-580)
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- 抗原 See all Metabotropic Glutamate Receptor 5 (GRM5) 抗体
- Metabotropic Glutamate Receptor 5 (GRM5) (Glutamate Receptor, Metabotropic 5 (GRM5))
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抗原表位
- AA 458-580
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适用
- 人
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This Metabotropic Glutamate Receptor 5 antibody is un-conjugated
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应用范围
- Immunohistochemistry (IHC), ELISA, Immunocytochemistry (ICC)
- 原理
- GRM5 Antibody
- 纯化方法
- Purified antibody
- 免疫原
- Purified recombinant fragment of human GRM5 (AA: 458-580) expressed in E. Coli.
- 克隆位点
- 1A11D10
- 亚型
- IgG1
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- 应用备注
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ELISA: 1/10000
ICC: 1/200 - 1/1000
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- Purified antibody in PBS with 0.05 % sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
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- 抗原
- Metabotropic Glutamate Receptor 5 (GRM5) (Glutamate Receptor, Metabotropic 5 (GRM5))
- 别名
- GRM5 (GRM5 产品)
- 别名
- GPRC1E antibody, MGLUR5 antibody, mGlu5 antibody, mGluR5 antibody, mGlur5 antibody, 6430542K11Rik antibody, AI850523 antibody, Glu5R antibody, Gprc1e antibody, mGluR5b antibody, glutamate receptor, metabotropic 5 antibody, glutamate metabotropic receptor 5 antibody, GRM5 antibody, Grm5 antibody
- 背景
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Description: This gene encodes a member of the G-protein coupled receptor 3 protein family. The encoded protein is a metabatropic glutamate receptor, whose signaling activates a phosphatidylinositol-calcium second messenger system. This protein may be involved in the regulation of neural network activity and synaptic plasticity. Glutamatergic neurotransmission is involved in most aspects of normal brain function and can be perturbed in many neuropathologic conditions. A pseudogene of this gene has been defined on chromosome 11. Alternative splicing results in multiple transcript variants.
Aliases: mGlu5, GPRC1E, MGLUR5, PPP1R86
- 分子量
- 132.5kDa
- 基因ID
- 2915
- HGNC
- 2915
- UniProt
- P41594
- 途径
- Regulation of G-Protein Coupled Receptor Protein Signaling, Regulation of long-term Neuronal Synaptic Plasticity
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