Metabotropic Glutamate Receptor 3 抗体 (AA 433-576)
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- 抗原 See all Metabotropic Glutamate Receptor 3 (GRM3) 抗体
- Metabotropic Glutamate Receptor 3 (GRM3) (Glutamate Receptor, Metabotropic 3 (GRM3))
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抗原表位
- AA 433-576
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适用
- 人
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This Metabotropic Glutamate Receptor 3 antibody is un-conjugated
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应用范围
- ELISA, Immunohistochemistry (IHC), Flow Cytometry (FACS), Immunocytochemistry (ICC)
- 原理
- GRM3 Antibody
- 纯化方法
- Purified antibody
- 免疫原
- Purified recombinant fragment of human GRM3 (AA: 433-576) expressed in E. Coli.
- 克隆位点
- 7A5A6
- 亚型
- IgG2a
- Top Product
- Discover our top product GRM3 Primary Antibody
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- 应用备注
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ELISA: 1/10000
FCM: 1/200 - 1/400
ICC: 1/200 - 1/1000
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- Purified antibody in PBS with 0.05 % sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
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- 抗原
- Metabotropic Glutamate Receptor 3 (GRM3) (Glutamate Receptor, Metabotropic 3 (GRM3))
- 别名
- GRM3 (GRM3 产品)
- 别名
- GLUR3 antibody, GPRC1C antibody, MGLUR3 antibody, mGlu3 antibody, 0710001G23Rik antibody, Gprc1c antibody, mGluR3 antibody, glutamate metabotropic receptor 3 antibody, glutamate receptor, metabotropic 3 antibody, GRM3 antibody, Grm3 antibody
- 背景
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Description: L-glutamate is the major excitatory neurotransmitter in the central nervous system and activates both ionotropic and metabotropic glutamate receptors. Glutamatergic neurotransmission is involved in most aspects of normal brain function and can be perturbed in many neuropathologic conditions. The metabotropic glutamate receptors are a family of G protein-coupled receptors, that have been divided into 3 groups on the basis of sequence homology, putative signal transduction mechanisms, and pharmacologic properties. Group I includes GRM1 and GRM5 and these receptors have been shown to activate phospholipase C. Group II includes GRM2 and GRM3 while Group III includes GRM4, GRM6, GRM7 and GRM8. Group II and III receptors are linked to the inhibition of the cyclic AMP cascade but differ in their agonist selectivities.
Aliases: GLUR3, mGlu3, GPRC1C, MGLUR3
- 分子量
- 99kDa
- 基因ID
- 2913
- HGNC
- 2913
- UniProt
- Q14832
- 途径
- cAMP Metabolic Process, Synaptic Membrane
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