GRM2 抗体 (AA 414-558)
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- 抗原 See all GRM2 抗体
- GRM2 (Glutamate Receptor, Metabotropic 2 (GRM2))
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抗原表位
- AA 414-558
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适用
- 人
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This GRM2 antibody is un-conjugated
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应用范围
- ELISA, Flow Cytometry (FACS)
- 原理
- GRM2 Antibody
- 纯化方法
- Purified antibody
- 免疫原
- Purified recombinant fragment of human GRM2 (AA: 414-558) expressed in E. Coli.
- 克隆位点
- 4A10B9
- 亚型
- IgG1
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- 应用备注
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ELISA: 1/10000
FCM: 1/200 - 1/400
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- Purified antibody in PBS with 0.05 % sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
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- 抗原
- GRM2 (Glutamate Receptor, Metabotropic 2 (GRM2))
- 别名
- GRM2 (GRM2 产品)
- 别名
- GLUR2 antibody, GPRC1B antibody, MGLUR2 antibody, mGlu2 antibody, 4930441L02Rik antibody, Gprc1b antibody, mGluR2 antibody, mGluR7 antibody, glutamate metabotropic receptor 2 antibody, glutamate receptor, metabotropic 2 antibody, GRM2 antibody, Grm2 antibody
- 背景
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Description: L-glutamate is the major excitatory neurotransmitter in the central nervous system and activates both ionotropic and metabotropic glutamate receptors. Glutamatergic neurotransmission is involved in most aspects of normal brain function and can be perturbed in many neuropathologic conditions. The metabotropic glutamate receptors are a family of G protein-coupled receptors, that have been divided into 3 groups on the basis of sequence homology, putative signal transduction mechanisms, and pharmacologic properties. Group I includes GRM1 and GRM5 and these receptors have been shown to activate phospholipase C. Group II includes GRM2 and GRM3 while Group III includes GRM4, GRM6, GRM7 and GRM8. Group II and III receptors are linked to the inhibition of the cyclic AMP cascade but differ in their agonist selectivities. Several transcript variants encoding different isoforms have been found for this gene.
Aliases: GLUR2, mGlu2, GPRC1B, MGLUR2
- 分子量
- 95.6kDa
- 基因ID
- 2912
- HGNC
- 2912
- UniProt
- Q14416
- 途径
- cAMP Metabolic Process, Dicarboxylic Acid Transport
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