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GRM2 抗体 (AA 414-558)

GRM2 适用: 人 ELISA, FACS 宿主: 小鼠 Monoclonal 4A10B9 unconjugated
产品编号 ABIN5611158
发货至: 中国
  • 抗原 See all GRM2 抗体
    GRM2 (Glutamate Receptor, Metabotropic 2 (GRM2))
    抗原表位
    • 15
    • 7
    • 5
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 414-558
    适用
    • 57
    • 54
    • 37
    • 16
    • 16
    • 13
    • 4
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    宿主
    • 67
    • 4
    • 1
    小鼠
    克隆类型
    • 64
    • 8
    单克隆
    标记
    • 27
    • 5
    • 4
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    This GRM2 antibody is un-conjugated
    应用范围
    • 31
    • 24
    • 19
    • 13
    • 12
    • 9
    • 9
    • 4
    • 3
    • 1
    • 1
    ELISA, Flow Cytometry (FACS)
    原理
    GRM2 Antibody
    纯化方法
    Purified antibody
    免疫原
    Purified recombinant fragment of human GRM2 (AA: 414-558) expressed in E. Coli.
    克隆位点
    4A10B9
    亚型
    IgG1
  • 应用备注

    ELISA: 1/10000

    FCM: 1/200 - 1/400

    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Purified antibody in PBS with 0.05 % sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
  • 抗原
    GRM2 (Glutamate Receptor, Metabotropic 2 (GRM2))
    别名
    GRM2 (GRM2 产品)
    别名
    GLUR2 antibody, GPRC1B antibody, MGLUR2 antibody, mGlu2 antibody, 4930441L02Rik antibody, Gprc1b antibody, mGluR2 antibody, mGluR7 antibody, glutamate metabotropic receptor 2 antibody, glutamate receptor, metabotropic 2 antibody, GRM2 antibody, Grm2 antibody
    背景

    Description: L-glutamate is the major excitatory neurotransmitter in the central nervous system and activates both ionotropic and metabotropic glutamate receptors. Glutamatergic neurotransmission is involved in most aspects of normal brain function and can be perturbed in many neuropathologic conditions. The metabotropic glutamate receptors are a family of G protein-coupled receptors, that have been divided into 3 groups on the basis of sequence homology, putative signal transduction mechanisms, and pharmacologic properties. Group I includes GRM1 and GRM5 and these receptors have been shown to activate phospholipase C. Group II includes GRM2 and GRM3 while Group III includes GRM4, GRM6, GRM7 and GRM8. Group II and III receptors are linked to the inhibition of the cyclic AMP cascade but differ in their agonist selectivities. Several transcript variants encoding different isoforms have been found for this gene.

    Aliases: GLUR2, mGlu2, GPRC1B, MGLUR2

    分子量
    95.6kDa
    基因ID
    2912
    HGNC
    2912
    UniProt
    Q14416
    途径
    cAMP Metabolic Process, Dicarboxylic Acid Transport
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