IL2 Receptor beta 抗体 (AA 27-240)
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- 抗原 See all IL2 Receptor beta (IL2RB) 抗体
- IL2 Receptor beta (IL2RB) (Interleukin 2 Receptor, beta (IL2RB))
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抗原表位
- AA 27-240
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适用
- 人
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This IL2 Receptor beta antibody is un-conjugated
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应用范围
- Flow Cytometry (FACS), ELISA
- 原理
- CD122 Antibody
- 纯化方法
- Purified antibody
- 免疫原
- Purified recombinant fragment of human CD122 (AA: 27-240) expressed in E. Coli.
- 克隆位点
- 1G11C6
- 亚型
- IgG2b
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- 应用备注
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ELISA: 1/10000
FCM: 1/200 - 1/400
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- Purified antibody in PBS with 0.05 % sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
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- 抗原
- IL2 Receptor beta (IL2RB) (Interleukin 2 Receptor, beta (IL2RB))
- 别名
- CD122 (IL2RB 产品)
- 别名
- IL2RB antibody, il-2rb antibody, CD122 antibody, IL15RB antibody, P70-75 antibody, IL2RBC antibody, IL-15Rbeta antibody, IL15Rbeta antibody, Il-2/15Rbeta antibody, Il-2Rbeta antibody, p70 antibody, interleukin 2 receptor subunit beta antibody, interleukin-2 receptor subunit beta antibody, interleukin 2 receptor, beta antibody, interleukin 2 receptor, beta chain antibody, IL2RB antibody, LOC510185 antibody, il2rb antibody, Il2rb antibody
- 背景
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Description: The interleukin 2 receptor, which is involved in T cell-mediated immune responses, is present in 3 forms with respect to ability to bind interleukin 2. The low affinity form is a monomer of the alpha subunit and is not involved in signal transduction. The intermediate affinity form consists of an alpha/beta subunit heterodimer, while the high affinity form consists of an alpha/beta/gamma subunit heterotrimer. Both the intermediate and high affinity forms of the receptor are involved in receptor-mediated endocytosis and transduction of mitogenic signals from interleukin 2. The protein encoded by this gene represents the beta subunit and is a type I membrane protein. The use of alternative promoters results in multiple transcript variants encoding the same protein. The protein is primarily expressed in the hematopoietic system. The use by some variants of an alternate promoter in an upstream long terminal repeat (LTR) results in placenta-specific expression.
Aliases: IL2RB, IL15RB, P70-75
- 分子量
- 61kDa
- 基因ID
- 3560
- HGNC
- 3560
- UniProt
- P14784
- 途径
- JAK/STAT Signaling, Growth Factor Binding
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