BCR 抗体 (AA 139-280)
-
- 抗原 See all BCR 抗体
- BCR (Breakpoint Cluster Region (BCR))
-
抗原表位
- AA 139-280
-
适用
- 人
-
宿主
- 小鼠
-
克隆类型
- 单克隆
-
标记
- This BCR antibody is un-conjugated
-
应用范围
- Western Blotting (WB), ELISA, Flow Cytometry (FACS)
- 原理
- BCR Antibody
- 纯化方法
- Purified antibody
- 免疫原
- Purified recombinant fragment of human BCR (AA: 139-280) expressed in E. Coli.
- 克隆位点
- 1E11G12
- 亚型
- IgG1
- Top Product
- Discover our top product BCR Primary Antibody
-
anti-Breakpoint Cluster Region (BCR) (AA 182-280) antibody
BCR 适用: 人 WB, ELISA, IF, PLA 宿主: 小鼠 Monoclonal 2E5 unconjugated
anti-Breakpoint Cluster Region (BCR) (pTyr360) antibodyBCR 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Breakpoint Cluster Region (BCR) (pTyr177) antibodyBCR 适用: 人, 小鼠 WB, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Breakpoint Cluster Region (BCR) (AA 1-300) antibodyBCR 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Breakpoint Cluster Region (BCR) (AA 1-1076) antibodyBCR 适用: 人 WB, PLA 宿主: 兔 Polyclonal unconjugated
anti-Breakpoint Cluster Region (BCR) (N-Term) antibodyBCR 适用: 人, 小鼠 WB, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Breakpoint Cluster Region (BCR) (AA 331-380), (pTyr360) antibodyBCR 适用: 人, 小鼠 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Breakpoint Cluster Region (BCR) (pTyr177) antibodyBCR 适用: 人 WB, ELISA, FACS, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Breakpoint Cluster Region (BCR) (pTyr360) antibodyBCR 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Breakpoint Cluster Region (BCR) (Ser178) antibodyBCR 适用: 人, 小鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
-
- 应用备注
-
ELISA: 1/10000
FCM: 1/200 - 1/400
- 限制
- 仅限研究用
-
- 状态
- Liquid
- 缓冲液
- Purified antibody in PBS with 0.05 % sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
-
- 抗原
- BCR (Breakpoint Cluster Region (BCR))
- 别名
- BCR (BCR 产品)
- 背景
-
Description: A reciprocal translocation between chromosomes 22 and 9 produces the Philadelphia chromosome, which is often found in patients with chronic myelogenous leukemia. The chromosome 22 breakpoint for this translocation is located within the BCR gene. The translocation produces a fusion protein which is encoded by sequence from both BCR and ABL, the gene at the chromosome 9 breakpoint. Although the BCR-ABL fusion protein has been extensively studied, the function of the normal BCR gene product is not clear. The protein has serine/threonine kinase activity and is a GTPase-activating protein for p21rac. Two transcript variants encoding different isoforms have been found for this gene.
Aliases: ALL, CML, PHL, BCR1, D22S11, D22S662
- 分子量
- 142.8kDa
- 基因ID
- 613
- HGNC
- 613
- UniProt
- P11274
- 途径
- Regulation of Leukocyte Mediated Immunity, Platelet-derived growth Factor Receptor Signaling
-
