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Adenosine A2a Receptor 抗体 (AA 274-412)

ADORA2A 适用: 人 ELISA, FACS, ICC 宿主: 小鼠 Monoclonal 6A6G11 unconjugated
产品编号 ABIN5611128
发货至: 中国
  • 抗原 See all Adenosine A2a Receptor (ADORA2A) 抗体
    Adenosine A2a Receptor (ADORA2A)
    抗原表位
    • 12
    • 9
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    AA 274-412
    适用
    • 77
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    • 9
    • 5
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    • 1
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    宿主
    • 70
    • 8
    • 2
    小鼠
    克隆类型
    • 74
    • 5
    • 1
    单克隆
    标记
    • 48
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    This Adenosine A2a Receptor antibody is un-conjugated
    应用范围
    • 63
    • 27
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    • 17
    • 12
    • 10
    • 8
    • 2
    • 2
    • 2
    • 1
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    ELISA, Flow Cytometry (FACS), Immunocytochemistry (ICC)
    原理
    ADORA2A Antibody
    纯化方法
    Purified antibody
    免疫原
    Purified recombinant fragment of human ADORA2A (AA: 274-412) expressed in E. Coli.
    克隆位点
    6A6G11
    亚型
    IgG2a
    Top Product
    Discover our top product ADORA2A Primary Antibody
  • 应用备注

    ELISA: 1/10000

    FCM: 1/200 - 1/400

    ICC: 1/100 - 1/500

    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Purified antibody in PBS with 0.05 % sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
  • 抗原
    Adenosine A2a Receptor (ADORA2A)
    别名
    ADORA2A (ADORA2A 产品)
    别名
    ADORA2A antibody, adora2a.1 antibody, zgc:194773 antibody, A2aR antibody, ADORA2 antibody, RDC8 antibody, A2AAR antibody, AA2AR antibody, A2ar antibody, ADENO antibody, Adora2l1 antibody, adora2a.2 antibody, zgc:193802 antibody, zgc:193822 antibody, adenosine A2a receptor antibody, adenosine A2a receptor a antibody, adenosine A2a receptor L homeolog antibody, adenosine A2a receptor b antibody, ADORA2A antibody, Adora2a antibody, adora2aa antibody, adora2a.L antibody, adora2a antibody, adora2ab antibody
    背景

    Description: This gene encodes a member of the guanine nucleotide-binding protein (G protein)-coupled receptor (GPCR) superfamily, which is subdivided into classes and subtypes. The receptors are seven-pass transmembrane proteins that respond to extracellular cues and activate intracellular signal transduction pathways. This protein, an adenosine receptor of A2A subtype, uses adenosine as the preferred endogenous agonist and preferentially interacts with the G(s) and G(olf) family of G proteins to increase intracellular cAMP levels. It plays an important role in many biological functions, such as cardiac rhythm and circulation, cerebral and renal blood flow, immune function, pain regulation, and sleep. It has been implicated in pathophysiological conditions such as inflammatory diseases and neurodegenerative disorders. Alternative splicing results in multiple transcript variants. A read-through transcript composed of the upstream SPECC1L (sperm antigen with calponin homology and coiled-coil domains 1-like) and ADORA2A (adenosine A2a receptor) gene sequence has been identified, but it is thought to be non-coding.

    Aliases: A2aR, RDC8, ADORA2

    分子量
    44.7kDa
    基因ID
    135
    HGNC
    135
    UniProt
    P29274
    途径
    Neurotrophin Signaling Pathway, cAMP Metabolic Process, Synaptic Membrane, Feeding Behaviour, Cancer Immune Checkpoints
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