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eIF4EBP1 抗体 (pSer65)

EIF4EBP1 适用: 人 IHC, ELISA, FACS, ICC 宿主: 小鼠 Monoclonal 1E2E7 unconjugated
产品编号 ABIN5611114
发货至: 中国
  • 抗原 See all eIF4EBP1 (EIF4EBP1) 抗体
    eIF4EBP1 (EIF4EBP1) (Eukaryotic Translation Initiation Factor 4E Binding Protein 1 (EIF4EBP1))
    抗原表位
    • 25
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    pSer65
    适用
    • 208
    • 155
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    宿主
    • 225
    • 12
    • 4
    小鼠
    克隆类型
    • 213
    • 30
    单克隆
    标记
    • 103
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    This eIF4EBP1 antibody is un-conjugated
    应用范围
    • 198
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    • 22
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    Immunohistochemistry (IHC), ELISA, Flow Cytometry (FACS), Immunocytochemistry (ICC)
    原理
    Phospho-4E-BP1 (Ser65) Antibody
    纯化方法
    Purified antibody
    免疫原
    Synthesized peptide of human Phospho-4E-BP1 (Ser65).
    克隆位点
    1E2E7
    亚型
    IgG1
    Top Product
    Discover our top product EIF4EBP1 Primary Antibody
  • 应用备注

    ELISA: 1/10000

    FCM: 1/200 - 1/400

    ICC: 1/100 - 1/500

    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Purified antibody in PBS with 0.05 % sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
  • 抗原
    eIF4EBP1 (EIF4EBP1) (Eukaryotic Translation Initiation Factor 4E Binding Protein 1 (EIF4EBP1))
    别名
    4E-BP1 (EIF4EBP1 产品)
    背景

    Description: This gene encodes one member of a family of translation repressor proteins. The protein directly interacts with eukaryotic translation initiation factor 4E (eIF4E), which is a limiting component of the multisubunit complex that recruits 40S ribosomal subunits to the 5' end of mRNAs. Interaction of this protein with eIF4E inhibits complex assembly and represses translation. This protein is phosphorylated in response to various signals including UV irradiation and insulin signaling, resulting in its dissociation from eIF4E and activation of mRNA translation.

    Aliases: EIF4EBP1, BP-1, 4EBP1, 4E-BP1, PHAS-I

    分子量
    12.6kDa
    基因ID
    1978
    HGNC
    1978
    UniProt
    Q13541
    途径
    MAPK Pathway, PI3K-Akt Signaling, RTK signaling, AMPK Signaling, Regulation of Cell Size, BCR Signaling
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