aaat antibody, asct2 antibody, atbo antibody, m7v1 antibody, m7vs1 antibody, r16 antibody, rdrc antibody, AAAT antibody, ASCT2 antibody, ATBO antibody, M7V1 antibody, M7VS1 antibody, R16 antibody, RDRC antibody, Slc1a7 antibody, Asct2 antibody, H4-ASCT2 antibody, solute carrier family 1 (neutral amino acid transporter), member 5 antibody, solute carrier family 1 member 5 S homeolog antibody, solute carrier family 1 member 5 antibody, slc1a5 antibody, slc1a5.S antibody, SLC1A5 antibody, Slc1a5 antibody
背景
Solute Carrier Family 1 Member 5 (Slc1a5/ASCT2) belongs to a family of sodium dependent amino acid transporters. Slc1a5 has a preference for transporting zwitter ions. Slc1a5 also functions as a cell surface receptor for endogenously inherited retroviruses of cats, baboons and humans as well as for horizontally transmitted type-D simian retroviruses. In addition, it has been associated with increased metabolism in malignant tumors. In prostate carcinoma ASCT2 positivity is correlated with more aggressive biological behavior.Synonyms: ASCT2, ATB(0), Baboon M7 virus receptor, M7V1, Neutral amino acid transporter B(0), RD114/simian type D retrovirus receptor, RDR, RDRC, Sodium-dependent neutral amino acid transporter type 2, Solute carrier family 1 member 5