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Filamin A 抗体 (AA 1-838)

FLNA 适用: 人 WB, ELISA, IHC (p), PLA 宿主: 小鼠 Monoclonal 4E10-1B2 unconjugated
产品编号 ABIN560922
发货至: 中国
  • 抗原 See all Filamin A (FLNA) 抗体
    Filamin A (FLNA) (Filamin A, alpha (FLNA))
    抗原表位
    • 15
    • 15
    • 13
    • 7
    • 6
    • 5
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1-838
    适用
    • 103
    • 33
    • 28
    • 3
    • 1
    • 1
    宿主
    • 96
    • 6
    • 1
    小鼠
    克隆类型
    • 88
    • 15
    单克隆
    标记
    • 44
    • 7
    • 5
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    This Filamin A antibody is un-conjugated
    应用范围
    • 52
    • 31
    • 28
    • 28
    • 27
    • 24
    • 12
    • 11
    • 7
    • 5
    • 3
    • 3
    • 2
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Proximity Ligation Assay (PLA)
    原理
    Mouse monoclonal antibody raised against a full length recombinant FLNA.
    序列
    MPSGKVAQPT ITDNKDGTVT VRYAPSEAGL HEMDIRYDNM HIPGSPLQFY VDYVNCGHVT AYGPGLTHGV VNKPATFTVN TKDAGEGGLS LAIEGPSKAE ISCTDNQDGT CSVSYLPVLP GDYSILVKYN EQHVPGSPFT ARVTGDDSMR MSHLKVGSAA DIPINISETD LSLLTATVVP PSGREEPCLL KRLRNGHVGI SFVPKETGEH LVHVKKNGQH VASSPIPVVI SQSEIGDASR VRVSGQGLHE GHTFEPAEFI IDTRDAGYGG LSLSIEGPSK VDINTEDLED GTCRVTYCPT EPGNYIINIK FADQHVPGSP FSVKVTGEGR VKESITRRRR APSVANVGSH CDLSLKIPEI SIQDMTAQVT SPSGKTHEAE IVEGENHTYC IRFVPAEMGT HTVSVKYKGQ HVPGSPFQFT VGPLGEGGAH KVRAGGPGLE RAEAGVPAEF SIWTREAGAG GLAIAVEGPS KAEISFEDRK DGSCGVAYVV QEPGDYEVSV KFNEEHIPDS PFVVPVASPS GDARRLTVSS LQESGLKVNQ PASFAVSLNG AKGAIDAKVH SPSGALEECY VTEIDQDKYA VRFIPRENGV YLIDVKFNGT HIPGSPFKIR VGEPGHGGDP GLVSAYGAGL EGGVTGNPAE FVVNTSNAGA GALSVTIDGP SKVKMDCQEC PEGYRVTYTP MAPGSYLISI KYGGPYHIGG SPFKAKVTGP RLVSNHSLHE TSSVFVDSLT KATCAPQHGA PGPGPADASK VVAKGLGLSK AYVGQKSSFT VDCSKAGNNM LLVGVHGPRT PCEEILVKHV GSRLYSVSYL LKDKGEYTLV VKWGDEHIPG SPYRVVVP
    交叉反应
    产品特性
    Antibody Reactive Against Recombinant Protein.
    免疫原
    FLNA (AAH14654, 1 a.a. ~ 838 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
    克隆位点
    4E10-1B2
    亚型
    IgG1
    Top Product
    Discover our top product FLNA Primary Antibody
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 缓冲液
    In 1x PBS, pH 7.4
    注意事项
    Aliquot to avoid repeated freezing and thawing.
    储存条件
    -20 °C
    储存方法
    Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
  • Mingione, Verdelli, Ferrero, Vaira, Guarnieri, Scillitani, Vicentini, Balza, Beretta, Terranegra, Vezzoli, Soldati, Corbetta: "Filamin A is reduced and contributes to the CASR sensitivity in human parathyroid tumors." in: Journal of molecular endocrinology, Vol. 58, Issue 2, pp. 91-103, (2016) (PubMed).

    Parrini, Mei, Pisanti, Catarzi, Pucatti, Bianchini, Mascalchi, Bertini, Morrone, Cavaliere, Guerrini: "Familial periventricular nodular heterotopia, epilepsy and Melnick-Needles Syndrome caused by a single FLNA mutation with combined gain-of-function and loss-of-function effects." in: Journal of medical genetics, Vol. 52, Issue 6, pp. 405-12, (2015) (PubMed).

    Bézie, Picarda, Tesson, Renaudin, Durand, Ménoret, Mérieau, Chiffoleau, Guillonneau, Caron, Anegon: "Fibrinogen-like protein 2/fibroleukin induces long-term allograft survival in a rat model through regulatory B cells." in: PLoS ONE, Vol. 10, Issue 3, pp. e0119686, (2015) (PubMed).

    Peverelli, Giardino, Treppiedi, Vitali, Cambiaghi, Locatelli, Lasio, Spada, Lania, Mantovani: "Filamin A (FLNA) plays an essential role in somatostatin receptor 2 (SST2) signaling and stabilization after agonist stimulation in human and rat somatotroph tumor cells." in: Endocrinology, Vol. 155, Issue 8, pp. 2932-41, (2014) (PubMed).

    Oegema, Hulst, Theuns-Valks, van Unen, Schot, Mancini, Schipper, de Wit, Sibbles, de Coo, Nanninga, Hofstra, Halley, Brooks: "Novel no-stop FLNA mutation causes multi-organ involvement in males." in: American journal of medical genetics. Part A, Vol. 161A, Issue 9, pp. 2376-84, (2013) (PubMed).

    Sakane, Alamir Mahmoud Abdallah, Nakano, Honda, Kitamura, Imoto, Matsushita, Sasaki: "Junctional Rab13-binding protein (JRAB) regulates cell spreading via filamins." in: Genes to cells : devoted to molecular & cellular mechanisms, Vol. 18, Issue 9, pp. 810-22, (2013) (PubMed).

    Peverelli, Mantovani, Vitali, Elli, Olgiati, Ferrero, Laws, Della Mina, Villa, Beck-Peccoz, Spada, Lania: "Filamin-A is essential for dopamine d2 receptor expression and signaling in tumorous lactotrophs." in: The Journal of clinical endocrinology and metabolism, Vol. 97, Issue 3, pp. 967-77, (2012) (PubMed).

    Valente, Logan, Mougou-Zerelli, Lee, Silhavy, Brancati, Iannicelli, Travaglini, Romani, Illi, Adams, Szymanska, Mazzotta, Lee, Tolentino, Swistun, Salpietro, Fede, Gabriel, Russ, Cibulskis, Sougnez et al.: "Mutations in TMEM216 perturb ciliogenesis and cause Joubert, Meckel and related syndromes. ..." in: Nature genetics, Vol. 42, Issue 7, pp. 619-25, (2010) (PubMed).

  • 抗原
    Filamin A (FLNA) (Filamin A, alpha (FLNA))
    别名
    FLNA (FLNA 产品)
    别名
    ABP-280 antibody, ABPX antibody, CSBS antibody, CVD1 antibody, FLN antibody, FLN-A antibody, FLN1 antibody, FMD antibody, MNS antibody, NHBP antibody, OPD antibody, OPD1 antibody, OPD2 antibody, XLVD antibody, XMVD antibody, fb98b06 antibody, wu:fb98b06 antibody, wu:fd09g03 antibody, wu:fd49a06 antibody, Dilp2 antibody, F730004A14Rik antibody, Fln1 antibody, filamin-1 antibody, RGD1560614 antibody, MGC147094 antibody, CG3937 antibody, Cher antibody, Dmel\\CG3937 antibody, Fil antibody, joy antibody, sko antibody, filamin A antibody, filamin A, alpha (actin binding protein 280) antibody, filamin, alpha antibody, filamin-A antibody, cheerio antibody, FLNA antibody, flna antibody, Flna antibody, LOC587317 antibody, cher antibody, LOC100380643 antibody
    背景
    Full Gene Name: filamin A, alpha (actin binding protein 280)
    Synonyms: ABP-280,ABPX,DKFZp434P031,FLN,FLN1,FMD,MNS,NHBP,OPD,OPD1,OPD2
    基因ID
    2316
    途径
    TCR Signaling, Maintenance of Protein Location
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