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CTH 抗体 (AA 1-405)

Name: CTH 抗体 (AA 1-405)
SKU: ABIN560521
Availability: OutOfStock

CTH 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 4E1-1B7 unconjugated

Western Blot analysis of CTH expression in transfected 293T cell line by CTH monoclonal antibody (M01), clone 4E1-1B7. (CTH 抗体 (AA 1-405))

Detection limit for recombinant GST tagged CTH is approximately 1ng/ml as a capture antibody. (CTH 抗体 (AA 1-405))

ELISA

CTH monoclonal antibody (M01), clone 4E1-1B7. (CTH 抗体 (AA 1-405))

Western Blot detection against Immunogen (70. (CTH 抗体 (AA 1-405))

5 images

(21 references)

产品编号 ABIN560521

发货至: 中国

Datasheet as PDF

抗原 See all CTH 抗体

CTH (Cystathionase (Cystathionine gamma-Lyase) (CTH))
抗原表位
12

6

3

2

2

2

1

1

1

1

1
AA 1-405
适用
56

34

33

5

4

3

3

3

2

2

2

1
人
宿主
51

9
小鼠
Compatible Secondaries
克隆类型
51

9
单克隆
标记
31

4

3

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
This CTH antibody is un-conjugated
应用范围
44

16

13

10

9

5

5

5

4

3

2

2
Western Blotting (WB), ELISA

原理

Mouse monoclonal antibody raised against a full length recombinant CTH.

序列

MQEKDASSQG FLPHFQHFAT QAIHVGQDPE QWTSRAVVPP ISLSTTFKQG APGQHSGFEY SRSGNPTRNC LEKAVAALDG AKYCLAFASG LAATVTITHL LKAGDQIICM DDVYGGTNRY FRQVASEFGL KISFVDCSKI KLLEAAITPE TKLVWIETPT NPTQKVIDIE GCAHIVHKHG DIILVVDNTF MSPYFQRPLA LGADISMYSA TKYMNGRSDV VMGLVSVNCE SLHNRLRFLQ NSLGAVPSPI DCYLCNRGLK TLHVRMEKHF KNGMAVAQFL ESNPWVEKVI YPGLPSHPQH ELVKRQCTGC TGMVTFYIKG TLQHAEIFLK NLKLFTLAES LGGFESLAEL PAIMTHASVL KNDRDVLGIS DTLIRLSVGL EDEEDLLEDL DQALKAAHPP SGSHS

交叉反应

豚鼠, 人, 大鼠

产品特性

Antibody Reactive Against Recombinant Protein.

免疫原

CTH (AAH15807, 1 a.a. ~ 405 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

克隆位点

4E1-1B7

亚型

IgG1
anti-Cystathionase (Cystathionine gamma-Lyase) (CTH) (AA 1-405) antibody
CTH 适用: 人 WB, ELISA, IHC (p) 宿主: 小鼠 Monoclonal S51 unconjugated

anti-Cystathionase (Cystathionine gamma-Lyase) (CTH) antibody
CTH 适用: 人, 小鼠, 大鼠 WB, IF (p), IHC (p) 宿主: 兔 Polyclonal unconjugated

anti-Cystathionase (Cystathionine gamma-Lyase) (CTH) (AA 1-70) antibody
CTH 适用: 人 WB, IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated

anti-Cystathionase (Cystathionine gamma-Lyase) (CTH) (AA 1-405) antibody
CTH 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated

anti-Cystathionase (Cystathionine gamma-Lyase) (CTH) (AA 1-405) antibody
CTH 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated

anti-Cystathionase (Cystathionine gamma-Lyase) (CTH) (AA 281-330) antibody
CTH 适用: 人 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated

anti-Cystathionase (Cystathionine gamma-Lyase) (CTH) (AA 316-331), (C-Term) antibody
CTH 适用: 人, 大鼠 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated

anti-Cystathionase (Cystathionine gamma-Lyase) (CTH) (AA 181-398) antibody
CTH 适用: 小鼠, 大鼠 WB 宿主: 兔 Polyclonal unconjugated

anti-Cystathionase (Cystathionine gamma-Lyase) (CTH) (C-Term) antibody
CTH 适用: 人, 小鼠, 大鼠, 犬, 兔, Cow, 斑马鱼, 豚鼠, 马 WB, IHC 宿主: 兔 Polyclonal unconjugated

anti-Cystathionase (Cystathionine gamma-Lyase) (CTH) (N-Term) antibody
CTH 适用: 人, 小鼠, 大鼠, 犬, 兔, Cow, 斑马鱼, 豚鼠, 马, Pig WB 宿主: 兔 Polyclonal unconjugated

应用备注

Optimal working dilution should be determined by the investigator.

限制

仅限研究用
缓冲液

In 1x PBS, pH 7.4

注意事项

Aliquot to avoid repeated freezing and thawing.

储存条件

-20 °C

储存方法

Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
Li, Li, Du, Wang, You, Wang, Xu, Cheng, Cao, Liu, Hu: "Homocysteine Triggers Inflammatory Responses in Macrophages through Inhibiting CSE-H2S Signaling via DNA Hypermethylation of CSE Promoter." in: International journal of molecular sciences, Vol. 16, Issue 6, pp. 12560-77, (2015) (PubMed).

Xu, Du, Li, Xu, Wang, You, Liu, Wang, Cao, Liu, Hu: "Statins upregulate cystathionine ?-lyase transcription and H2S generation via activating Akt signaling in macrophage." in: Pharmacological research : the official journal of the Italian Pharmacological Society, Vol. 87, pp. 18-25, (2014) (PubMed).

Ida, Sawa, Ihara, Tsuchiya, Watanabe, Kumagai, Suematsu, Motohashi, Fujii, Matsunaga, Yamamoto, Ono, Devarie-Baez, Xian, Fukuto, Akaike: "Reactive cysteine persulfides and S-polythiolation regulate oxidative stress and redox signaling." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 111, Issue 21, pp. 7606-11, (2014) (PubMed).

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Badiei, Rivers-Auty, Ang, Bhatia: "Inhibition of hydrogen sulfide production by gene silencing attenuates inflammatory activity of LPS-activated RAW264.7 cells." in: Applied microbiology and biotechnology, Vol. 97, Issue 17, pp. 7845-52, (2013) (PubMed).

Kasparek, Linden, Farrugia, Sarr: "Hydrogen sulfide modulates contractile function in rat jejunum." in: The Journal of surgical research, Vol. 175, Issue 2, pp. 234-42, (2012) (PubMed).

Yang, Pei, Cao, Wang: "MicroRNA-21 represses human cystathionine gamma-lyase expression by targeting at specificity protein-1 in smooth muscle cells." in: Journal of cellular physiology, Vol. 227, Issue 9, pp. 3192-200, (2012) (PubMed).

Yang, Li, Tang, Wu, Zhao, Cao, Xu, Wang: "Increased neointimal formation in cystathionine gamma-lyase deficient mice: role of hydrogen sulfide in ?5?1-integrin and matrix metalloproteinase-2 expression in smooth muscle cells." in: Journal of molecular and cellular cardiology, Vol. 52, Issue 3, pp. 677-88, (2012) (PubMed).

Dufton, Natividad, Verdu, Wallace: "Hydrogen sulfide and resolution of acute inflammation: A comparative study utilizing a novel fluorescent probe." in: Scientific reports, Vol. 2, pp. 499, (2012) (PubMed).

Wu, Teng, Yang, Wu, Wang: "Hydrogen sulfide inhibits the translational expression of hypoxia-inducible factor-1?." in: British journal of pharmacology, Vol. 167, Issue 7, pp. 1492-505, (2012) (PubMed).

Fu, Zhang, Yang, Wang: "Is cystathionine gamma-lyase protein expressed in the heart?" in: Biochemical and biophysical research communications, Vol. 428, Issue 4, pp. 469-74, (2012) (PubMed).

Holwerda, Bos, Rajakumar, Ris-Stalpers, van Pampus, Timmer, Erwich, Faas, van Goor, Lely: "Hydrogen sulfide producing enzymes in pregnancy and preeclampsia." in: Placenta, Vol. 33, Issue 6, pp. 518-21, (2012) (PubMed).

Yang, Pei, Teng, Cao, Wang: "Specificity protein-1 as a critical regulator of human cystathionine gamma-lyase in smooth muscle cells." in: The Journal of biological chemistry, Vol. 286, Issue 30, pp. 26450-60, (2011) (PubMed).

Li, Mao, Hei, Zhang, Wen, Zhang, Qiu, Qiao: "Protective role of hydrogen sulfide against noise-induced cochlear damage: a chronic intracochlear infusion model." in: PLoS ONE, Vol. 6, Issue 10, pp. e26728, (2011) (PubMed).

Martin, McKnight, Dicay, Coffin, Ferraz, Wallace: "Hydrogen sulphide synthesis in the rat and mouse gastrointestinal tract." in: Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver, Vol. 42, Issue 2, pp. 103-9, (2010) (PubMed).

Feng, Chen, Zhao, Tang, Jiang, Geng: "Hydrogen sulfide from adipose tissue is a novel insulin resistance regulator." in: Biochemical and biophysical research communications, Vol. 380, Issue 1, pp. 153-9, (2009) (PubMed).

Wallace, Vong, McKnight, Dicay, Martin: "Endogenous and exogenous hydrogen sulfide promotes resolution of colitis in rats." in: Gastroenterology, Vol. 137, Issue 2, pp. 569-78, 578.e1, (2009) (PubMed).

Fu, Liu, Geng, Fang, Tang: "Hydrogen sulfide protects rat lung from ischemia-reperfusion injury." in: Life sciences, Vol. 82, Issue 23-24, pp. 1196-202, (2008) (PubMed).

Wallace, Dicay, McKnight, Martin: "Hydrogen sulfide enhances ulcer healing in rats." in: FASEB journal : official publication of the Federation of American Societies for Experimental Biology, Vol. 21, Issue 14, pp. 4070-6, (2007) (PubMed).

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抗原

CTH (Cystathionase (Cystathionine gamma-Lyase) (CTH))

别名

CTH (CTH 产品)

背景

Full Gene Name: cystathionase (cystathionine gamma-lyase)
Synonyms: MGC9471

基因ID

1491

途径

ER-Nucleus Signaling, Warburg Effect