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CBS 抗体 (AA 1-100)

Name: CBS 抗体 (AA 1-100)
SKU: ABIN7489109
Availability: OutOfStock

This anti-CBS antibody is a 小鼠单克隆 antibody detecting CBS in WB, ELISA, IHC (p), IP 和 RNAi. Suitable for 人. This Primary Antibody has been cited in 38+ publications.

Western Blot detection against Immunogen (36. (CBS 抗体 (AA 1-100))

Immunoprecipitation of CBS transfected lysate using anti-CBS monoclonal antibody and Protein A Magnetic Bead , and immunoblotted with CBS MaxPab rabbit polyclonal antibody. (CBS 抗体 (AA 1-100))

Immunoperoxidase of monoclonal antibody to CBS on formalin-fixed paraffin-embedded human hepatocellular carcinoma. (CBS 抗体 (AA 1-100))

ISt

CBS monoclonal antibody (M01), clone 3E1 Western Blot analysis of CBS expression in HeLa . (CBS 抗体 (AA 1-100))

Western Blot analysis of CBS expression in transfected 293T cell line by CBS monoclonal antibody (M01), clone 3E1. (CBS 抗体 (AA 1-100))

CBS monoclonal antibody (M01), clone 3E1. (CBS 抗体 (AA 1-100))

Western blot analysis of CBS over-expressed 293 cell line, cotransfected with CBS Validated Chimera RNAi (Lane 2) or non-transfected control (Lane 1). (CBS 抗体 (AA 1-100))

Detection limit for recombinant GST tagged CBS is approximately 0. (CBS 抗体 (AA 1-100))

ELISA

8 images

(38 references)

产品编号 ABIN7489109

发货至: 中国

Datasheet as PDF

Quick Overview for CBS 抗体 (AA 1-100) (ABIN7489109)

抗原

See all CBS 抗体

CBS (Cystathionine-beta-Synthase (CBS))

适用

人

宿主

小鼠

克隆类型

单克隆

标记

This CBS antibody is un-conjugated

应用范围

Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunoprecipitation (IP), RNA Interference (RNAi)

克隆位点

3E1

抗原表位
15

9

7

6

4

3

3

3

2

2

2

1

1

1

1

1

1

1

1

1
AA 1-100

原理

Mouse monoclonal antibody raised against a partial recombinant CBS.

序列

MPSETPQAEV GPTGCPHRSG PHSAKGSLEK GSPEDKEAKE PLWIRPDAPS RCTWQLGRPA SESPHHHTAP AKSPKILPDI LKKIGDTPMV RINKIGKKFG

交叉反应

人, 大鼠

产品特性

Antibody Reactive Against Recombinant Protein.

免疫原

CBS (NP_000062, 1 a.a. ~ 100 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

亚型

IgG2a
anti-Cystathionine-beta-Synthase (CBS) (AA 252-551) antibody
CBS 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated

anti-Cystathionine-beta-Synthase (CBS) (AA 104-133), (N-Term) antibody
CBS 适用: 人, 小鼠 WB, IF, IHC (p), FACS 宿主: 兔 Polyclonal RB22961 unconjugated

anti-Cystathionine-beta-Synthase (CBS) (AA 1-100) antibody
CBS 适用: 人 WB, ELISA, IF, IHC (p) 宿主: 小鼠 Monoclonal 6A9 unconjugated

anti-Cystathionine-beta-Synthase (CBS) (N-Term) antibody
CBS 适用: 人, 小鼠, 大鼠, 犬, Cow, 豚鼠, 马, 兔, Saccharomyces cerevisiae, 斑马鱼 WB, IHC 宿主: 兔 Polyclonal unconjugated

anti-Cystathionine-beta-Synthase (CBS) (AA 1-413) antibody
CBS 适用: 人 WB, ELISA, IHC, IF, IP 宿主: 兔 Polyclonal unconjugated

anti-Cystathionine-beta-Synthase (CBS) antibody
CBS 适用: 人 WB, IHC, IF 宿主: 兔 Monoclonal unconjugated

anti-Cystathionine-beta-Synthase (CBS) antibody
KO Validated CBS 适用: 人 WB, IF, IHC (p), IP, ICC 宿主: 兔 Polyclonal unconjugated

anti-Cystathionine-beta-Synthase (CBS) (AA 301-330) antibody
CBS 适用: 人, 小鼠, 大鼠 WB, IF, IHC (p), FACS 宿主: 兔 Polyclonal RB21183 unconjugated

anti-Cystathionine-beta-Synthase (CBS) (AA 1-100) antibody
CBS 适用: 人 WB, ELISA, IF, IP 宿主: 小鼠 Monoclonal 3D10 unconjugated

anti-Cystathionine-beta-Synthase (CBS) (AA 1-551) antibody
CBS 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated

应用备注

Optimal working dilution should be determined by the investigator.

限制

仅限研究用
缓冲液

In 1x PBS, pH 7.4

注意事项

Aliquot to avoid repeated freezing and thawing.

储存条件

-20 °C

储存方法

Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
Shang, Siow, Isaak, O: "Downregulation of Glutathione Biosynthesis Contributes to Oxidative Stress and Liver Dysfunction in Acute Kidney Injury." in: Oxidative medicine and cellular longevity, Vol. 2016, pp. 9707292, (2016) (PubMed).

Ohmura, Hishiki, Yamamoto, Nakanishi, Kubo, Tsuchihashi, Tamada, Toue, Kabe, Saya, Suematsu: "Impacts of CD44 knockdown in cancer cells on tumor and host metabolic systems revealed by quantitative imaging mass spectrometry." in: Nitric oxide : biology and chemistry / official journal of the Nitric Oxide Society, Vol. 46, pp. 102-13, (2015) (PubMed).

Yuan, Tang, Lu, Zhou, Zhu, Zhou, Zhang, Hu, Xu: "TLR4 upregulates CBS expression through NF-κB activation in a rat model of irritable bowel syndrome with chronic visceral hypersensitivity." in: World journal of gastroenterology, Vol. 21, Issue 28, pp. 8615-28, (2015) (PubMed).

Yang, Wu, Wood, Whiteman, Bian: "Hydrogen sulfide attenuates opioid dependence by suppression of adenylate cyclase/cAMP pathway." in: Antioxidants & redox signaling, Vol. 20, Issue 1, pp. 31-41, (2014) (PubMed).

Takano, Peng, Kumar, Luo, Hu, Shimoda, Suematsu, Prabhakar, Semenza: "Hypoxia-inducible factors regulate human and rat cystathionine ?-synthase gene expression." in: The Biochemical journal, Vol. 458, Issue 2, pp. 203-11, (2014) (PubMed).

Takano, Sarfraz, Gilkes, Chaturvedi, Xiang, Suematsu, Zagzag, Semenza: "Decreased expression of cystathionine ?-synthase promotes glioma tumorigenesis." in: Molecular cancer research : MCR, Vol. 12, Issue 10, pp. 1398-406, (2014) (PubMed).

Miyamoto, Otsuguro, Yamaguchi, Ito: "Contribution of cysteine aminotransferase and mercaptopyruvate sulfurtransferase to hydrogen sulfide production in peripheral neurons." in: Journal of neurochemistry, Vol. 130, Issue 1, pp. 29-40, (2014) (PubMed).

Ida, Sawa, Ihara, Tsuchiya, Watanabe, Kumagai, Suematsu, Motohashi, Fujii, Matsunaga, Yamamoto, Ono, Devarie-Baez, Xian, Fukuto, Akaike: "Reactive cysteine persulfides and S-polythiolation regulate oxidative stress and redox signaling." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 111, Issue 21, pp. 7606-11, (2014) (PubMed).

Du, Jin, Hong, Li, Wang, Xu, Wang, Zhang, Jia, Liu, Hu: "Downregulation of cystathionine ?-synthase/hydrogen sulfide contributes to rotenone-induced microglia polarization toward M1 type." in: Biochemical and biophysical research communications, Vol. 451, Issue 2, pp. 239-45, (2014) (PubMed).

Yamamoto, Takano, Ishiwata, Ohmura, Nagahata, Matsuura, Kamata, Sakamoto, Nakanishi, Kubo, Hishiki, Suematsu: "Reduced methylation of PFKFB3 in cancer cells shunts glucose towards the pentose phosphate pathway." in: Nature communications, Vol. 5, pp. 3480, (2014) (PubMed).

Rashid, Heer, Garle, Alexander, Roberts: "Hydrogen sulphide-induced relaxation of porcine peripheral bronchioles." in: British journal of pharmacology, Vol. 168, Issue 8, pp. 1902-10, (2013) (PubMed).

Hwang, Sarna, Siow, O: "High-fat diet stimulates hepatic cystathionine β-synthase and cystathionine γ-lyase expression." in: Canadian journal of physiology and pharmacology, Vol. 91, Issue 11, pp. 913-9, (2013) (PubMed).

Yang, Zhao, Ju, Mani, Cao, Puukila, Khaper, Wu, Wang: "Hydrogen sulfide protects against cellular senescence via S-sulfhydration of Keap1 and activation of Nrf2." in: Antioxidants & redox signaling, Vol. 18, Issue 15, pp. 1906-19, (2013) (PubMed).

Shi, Zhang, Xiao, Hu, Xu: "Electroacupuncture suppresses mechanical allodynia and nuclear factor ? B signaling in streptozotocin-induced diabetic rats." in: CNS neuroscience & therapeutics, Vol. 19, Issue 2, pp. 83-90, (2013) (PubMed).

Liu, Luo, Liang, Xia, Xu, Chen, Chen: "Actions of hydrogen sulfide and ATP-sensitive potassium channels on colonic hypermotility in a rat model of chronic stress." in: PLoS ONE, Vol. 8, Issue 2, pp. e55853, (2013) (PubMed).

Zhang, Hu, Zhou, Hu, Wang, Chen, Xiao, Huang, Jiang, Xu: "Promoted interaction of nuclear factor-?B with demethylated cystathionine-?-synthetase gene contributes to gastric hypersensitivity in diabetic rats." in: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 33, Issue 21, pp. 9028-38, (2013) (PubMed).

Hu, Xu, Miao, Gao, Zhu, Zhou, Xiao, Xu: "Sensitization of sodium channels by cystathionine ?-synthetase activation in colon sensory neurons in adult rats with neonatal maternal deprivation." in: Experimental neurology, Vol. 248, pp. 275-85, (2013) (PubMed).

Kasparek, Linden, Farrugia, Sarr: "Hydrogen sulfide modulates contractile function in rat jejunum." in: The Journal of surgical research, Vol. 175, Issue 2, pp. 234-42, (2012) (PubMed).

Guo, Gai, Wang, Jin, Du, Jin: "Characterization of hydrogen sulfide and its synthases, cystathionine ?-synthase and cystathionine ?-lyase, in human prostatic tissue and cells." in: Urology, Vol. 79, Issue 2, pp. 483.e1-5, (2012) (PubMed).

Dufton, Natividad, Verdu, Wallace: "Hydrogen sulfide and resolution of acute inflammation: A comparative study utilizing a novel fluorescent probe." in: Scientific reports, Vol. 2, pp. 499, (2012) (PubMed).

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抗原

CBS (Cystathionine-beta-Synthase (CBS))

别名

CBS

背景

Full Gene Name: cystathionine-beta-synthase
Synonyms: HIP4

基因ID

875

NCBI登录号

NM_000071