SLC2A2 抗体 (C-Term)
(3 references)
Quick Overview for SLC2A2 抗体 (C-Term) (ABIN5596790)
抗原
See all SLC2A2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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Supplier Product No.
- 600-401-gn3
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Supplier
- Rockland
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原理
- Glut2 Antibody
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交叉反应 （详细）
- This affinity-purified Glut-2 antibody is directed against Glut2 protein.
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产品特性
- Synonyms: rabbit anti-Glut2 antibody, Solute carrier family 2 facilitated glucose transporter member 2, Glucose transporter type 2 liver, GLUT-2 antibody, Slc2a2, Glut 2 Antibody
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纯化方法
- The product was affinity purified from monospecific antiserum by immunoaffinity purification.
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过滤
- Sterile filtered
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免疫原
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Immunogen: This affinity-purified antibody was prepared from whole rabbit serum produced by repeated immunizations with a synthetic peptide corresponding to the C-terminal domain of mouse Glut2 protein.
Immunogen Type: Conjugated Peptide
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亚型
- IgG
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anti-Solute Carrier Family 2 (Facilitated Glucose Transporter), Member 2 (SLC2A2) antibody
SLC2A2 适用: 人 WB, IF 宿主: 兔 Monoclonal unconjugated
anti-Solute Carrier Family 2 (Facilitated Glucose Transporter), Member 2 (SLC2A2) (AA 496-508), (Intracellular) antibodySLC2A2 适用: 大鼠 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Solute Carrier Family 2 (Facilitated Glucose Transporter), Member 2 (SLC2A2) (AA 482-524) antibodySLC2A2 适用: 人, 大鼠, 小鼠 WB, ELISA, FACS, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Solute Carrier Family 2 (Facilitated Glucose Transporter), Member 2 (SLC2A2) (AA 235-485) antibodySLC2A2 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Solute Carrier Family 2 (Facilitated Glucose Transporter), Member 2 (SLC2A2) (N-Term) antibodySLC2A2 适用: 人, 大鼠, 小鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Solute Carrier Family 2 (Facilitated Glucose Transporter), Member 2 (SLC2A2) (AA 277-290) antibodySLC2A2 适用: 人 IHC, IHC (p) 宿主: 山羊 Polyclonal unconjugated
anti-Solute Carrier Family 2 (Facilitated Glucose Transporter), Member 2 (SLC2A2) (N-Term) antibodySLC2A2 适用: 人, 大鼠, 小鼠, Pig, Cow, 犬, 豚鼠, 马, 绵羊 WB 宿主: 兔 Polyclonal unconjugated
anti-Solute Carrier Family 2 (Facilitated Glucose Transporter), Member 2 (SLC2A2) (AA 31-60), (N-Term) antibodySLC2A2 适用: 人 WB, FACS 宿主: 兔 Polyclonal unconjugated
anti-Solute Carrier Family 2 (Facilitated Glucose Transporter), Member 2 (SLC2A2) (AA 31-60) antibodySLC2A2 适用: 人 WB, ELISA, FACS 宿主: 兔 Polyclonal unconjugated
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应用备注
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Immunohistochemistry Dilution: 4 μg/mL
Application Note: Anti-Glut-2 antibody has been tested for use in ELISA, immunohistochemistry, immunofluorescence, and by western blot. Specific conditions for reactivity should be optimized by the end user. Expect a band approximately 57.1 kDa in size corresponding to Glut2 protein by western blotting in the appropriate stimulated tissue or cell lysate or extract.
Western Blot Dilution: 1:500-1:1000
FLISA Dilution: 1
ELISA Dilution: 1:30,000-1:90:000
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1.0 mg/mL
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缓冲液
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Buffer: 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2
Stabilizer: None
Preservative: 0.01 % (w/v) Sodium Azide -
储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Store vial at -20° C prior to opening. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use.
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有效期
- 12 months
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: "Organic cation transporter 1 (OCT1) modulates multiple cardiometabolic traits through effects on hepatic thiamine content." in: PLoS biology, Vol. 16, Issue 4, pp. e2002907, (2019) (PubMed).
: "Reduced renal sympathetic nerve activity contributes to elevated glycosuria and improved glucose tolerance in hypothalamus-specific Pomc knockout mice." in: Molecular metabolism, Vol. 6, Issue 10, pp. 1274-1285, (2018) (PubMed).
: "Hypothalamic POMC Deficiency Improves Glucose Tolerance Despite Insulin Resistance by Increasing Glycosuria." in: Diabetes, Vol. 65, Issue 3, pp. 660-72, (2016) (PubMed).
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: "Organic cation transporter 1 (OCT1) modulates multiple cardiometabolic traits through effects on hepatic thiamine content." in: PLoS biology, Vol. 16, Issue 4, pp. e2002907, (2019) (PubMed).
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- SLC2A2 (Solute Carrier Family 2 (Facilitated Glucose Transporter), Member 2 (SLC2A2))
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别名
- Slc2a2
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背景
- Background: The Anti-Glut2 antibody was designed, produced, and validated as part of the Joy Cappel Young Investigator Award (JCYIA). The glucose transporter GLUT2 is a transmembrane carrier protein that allows protein facilitated glucose movement across cell membranes. GLUT2 is expressed in the plasma membranes of the liver, intestine, renal tubular cells, pancreatic islet beta cells, as well as in the portal and hypothalamic areas. Due to its low affinity and high capacity, GLUT2 transports dietary sugars, glucose, galactose and fructose in high concentrations, displaying large bidirectional fluxes in and out of cells. In pancreatic beta cells, GLUT2 is essential for glucose-stimulated insulin secretion. GLUT2 expression is necessary for the physiological control of glucose-sensitive genes, and its inactivation in the liver leads to impaired glucose-stimulated insulin secretion. In the nervous system, GLUT2-dependent glucose sensing regulates feeding, thermoregulation and pancreatic islet cell mass and function, as well as sympathetic and parasympathetic activities. In humans, inactivating mutations in GLUT2 cause Fanconi-Bickel syndrome, which is characterized by hepatomegaly and kidney disease. Anti-Glut2 is ideal for researchers interested in studying glucose transport mediated by Glut2 protein in the fields of diabetes, obesity, metabolism, and neuroscience research.
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基因ID
- 20526
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NCBI登录号
- NP_112474
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UniProt
- P14246
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途径
- Warburg Effect
抗原
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