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APOE 抗体

APOE 适用: 人, 大鼠 WB, ELISA, IHC, IP 宿主: 山羊 Polyclonal unconjugated
产品编号 ABIN5596681
发货至: 中国
  • 抗原 See all APOE 抗体
    APOE (Apolipoprotein E (APOE))
    适用
    • 108
    • 78
    • 55
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    人, 大鼠
    宿主
    • 106
    • 26
    • 13
    • 2
    山羊
    克隆类型
    • 109
    • 37
    多克隆
    标记
    • 61
    • 18
    • 11
    • 7
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    This APOE antibody is un-conjugated
    应用范围
    • 110
    • 59
    • 39
    • 39
    • 30
    • 25
    • 18
    • 12
    • 9
    • 8
    • 6
    • 5
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunoprecipitation (IP)
    交叉反应 (详细)
    Typically less than 1% cross-reactivity against other types of apoLipoprotein was detected by ELISA against purified standards. This antibody reacts with human apoLipoprotein E and has negligible cross-reactivity with Type A-1 A-II, B, C-I, C-II, C-III and J apoLipoproteins. Specific cross-reaction of anti-apoLipoprotein antibodies with antigens from other species has not been determined. Non-specific cross-reaction of anti-apoLipoprotein antibodies with other human serum proteins is negligible.
    纯化方法
    Anti-Apolipoprotein E has been prepared by immunoaffinity chromatography using immobilized antigens followed by extensive cross-adsorption against other apoLipoproteins and human serum proteins to remove any unwanted specificities.
    免疫原

    Immunogen: Apolipoprotein Type E was isolated from human plasma by density gradient centrifugation followed by HPLC purification.

    Immunogen Type: Native Protein

    亚型
    IgG
    Top Product
    Discover our top product APOE Primary Antibody
  • 应用备注

    Immunohistochemistry Dilution: 1:50 - 1:200

    Application Note: Apolipoprotein E antibodies have been used for indirect trapping ELISA for quantitation of antigen in serum using a standard curve, for immunoprecipitation and for western blotting for highly sensitive qualitative analysis.

    Western Blot Dilution: 1:500 - 1:2,000

    Immunoprecipitation Dilution: 1:100

    ELISA Dilution: 1:4,000 - 1:8,000

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1.0 mg/mL
    缓冲液

    Buffer: 0.125 M Sodium Borate, 0.075 M Sodium Chloride, 0.005 M EDTA, pH 8.0

    Stabilizer: None

    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Store vial at 4° C prior to opening. This product is stable at 4° C as an undiluted liquid. Dilute only prior to immediate use. For extended storage, mix with an equal volume of glycerol, aliquot contents and freeze at -20° C or below. Avoid cycles of freezing and thawing.
    有效期
    12 months
  • Lu, Yuan, Wang, Zhang, Yuan, Wu, Zhou, He, Lu, Chen, Fan, Liang, Cheng: "Spontaneous severe hypercholesterolemia and atherosclerosis lesions in rabbits with deficiency of low-density lipoprotein receptor (LDLR) on exon 7." in: EBioMedicine, Vol. 36, pp. 29-38, (2019) (PubMed).

  • 抗原
    APOE (Apolipoprotein E (APOE))
    别名
    APOLIPOPROTEIN E (APOE 产品)
    别名
    ad2 antibody, apoprotein antibody, im:7036787 antibody, wu:fb69a05 antibody, zgc:110064 antibody, apoe antibody, AI255918 antibody, AD2 antibody, LDLCQ5 antibody, LPG antibody, APOEA antibody, Apo-E antibody, apolipoprotein E antibody, apolipoprotein Ea antibody, apoe antibody, apoea antibody, Apoe antibody, APOE antibody
    背景

    Synonyms: Alzheimer disease 2 antibody, Apo E antibody, ApoE antibody, APOEA antibody, Apolipoprotein E3 antibody, ApolipoproteinE antibody, Apoprotein antibody

    Background: Anti Apolipoprotein E Antibody recognizes the gene product of APOE. Apolipoprotein E is found in the chylomicron and IDLs that binds to a specific receptor on liver cells and peripheral cells. Apolipoprotein E is essential for the normal catabolism of triglyceride-rich lipoprotein constituents. This antibody is suitable for cardiovascular research.

    Gene Name: APOE

    基因ID
    348
    UniProt
    P02649
    途径
    Regulation of Cell Size, Lipid Metabolism
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