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FIL1h 抗体

FIL1h 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN5564286
发货至: 中国
  • 抗原 See all FIL1h products
    FIL1h (Interleukin 1 eta (FIL1h))
    适用
    • 30
    • 1
    宿主
    • 24
    • 6
    克隆类型
    • 26
    • 4
    多克隆
    标记
    • 13
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
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    This FIL1h antibody is un-conjugated
    应用范围
    • 23
    • 18
    • 2
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB), ELISA
    特异性
    Recognizes human IL-36beta.
    交叉反应
    无交叉反应
    小鼠
    交叉反应 (详细)
    Does not cross-react with mouse IL-36beta and IL-36gamma.
    免疫原
    Recombinant human IL-36beta.
  • 限制
    仅限研究用
  • 状态
    Liquid
    浓度
    Lot specific
    缓冲液
    In PBS containing 10 % glycerol and 0.02 % sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Short Term Storage: +4°C
    Long Term Storage: -20°C
    Stable for at least 1 year after receipt when stored at -20°C.
    有效期
    12 months
  • 抗原
    FIL1h (Interleukin 1 eta (FIL1h))
    别名
    IL-36beta (FIL1h 产品)
    别名
    2310043N20Rik antibody, Il36b antibody, FIL1 antibody, FIL1-(ETA) antibody, FIL1H antibody, FILI-(ETA) antibody, IL-1F8 antibody, IL-1H2 antibody, IL1-ETA antibody, IL1F8 antibody, IL1H2 antibody, Il1f8 antibody, interleukin 1 family, member 8 antibody, interleukin 36 beta antibody, interleukin 36, beta antibody, Il1f8 antibody, IL36B antibody, Il36b antibody
    背景
    IL-36alpha (IL-1F6), IL-36beta (IL-1F8) and IL-36gamma (IL-1F9) bind to IL-36R (IL-1Rrp2) and IL-1RAcP, activating similar intracellular signals as IL-1. IL-36Ra inhibits the production of proinflammatory cytokines, including IL-12, IL-1beta, IL-6, TNF-alpha and IL-23 induced by IL-36 in BMDC and CD4 T cells. Skin and dendritic cells are targets of the IL-36 interleukins leading to a Th1 response. These cytokines may represent potential targets for immune-mediated inflammatory conditions or, alternatively, could be used as adjuvants in vaccination.
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