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IL1F10 抗体

IL1F10 适用: 人, 小鼠 ELISA, WB 宿主: 小鼠 Monoclonal Nhat-1 unconjugated
产品编号 ABIN5564279
发货至: 中国
  • 抗原 See all IL1F10 抗体
    IL1F10 (Interleukin 1 Family, Member 10 (Theta) (IL1F10))
    适用
    • 28
    • 10
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    人, 小鼠
    宿主
    • 18
    • 9
    • 1
    小鼠
    克隆类型
    • 18
    • 10
    单克隆
    标记
    • 11
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    This IL1F10 antibody is un-conjugated
    应用范围
    • 10
    • 9
    • 5
    • 1
    • 1
    ELISA, Western Blotting (WB)
    特异性
    Recognizes human and mouse IL-38.
    交叉反应
    人, 小鼠
    纯度
    >95 % (SDS-PAGE)
    免疫原
    Recombinant human IL-38.
    克隆位点
    Nhat-1
    亚型
    IgG2b
    Top Product
    Discover our top product IL1F10 Primary Antibody
  • 限制
    仅限研究用
  • 状态
    Liquid
    浓度
    Lot specific
    缓冲液
    In PBS containing 10 % glycerol and 0.02 % sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Short Term Storage: +4°C
    Long Term Storage: -20°C
    Stable for at least 1 year after receipt when stored at -20°C.
    有效期
    12 months
  • 抗原
    IL1F10 (Interleukin 1 Family, Member 10 (Theta) (IL1F10))
    别名
    IL-38 (IL1F10 产品)
    别名
    FIL1-theta antibody, IL-1HY2 antibody, IL-38 antibody, IL1-theta antibody, IL1HY2 antibody, interleukin 1 family, member 10 antibody, interleukin 1 family member 10 antibody, Il1f10 antibody, IL1F10 antibody
    背景
    IL-38 (IL-1F10) belongs to the IL-1 family of proteins. IL-38 is expressed in heart, placenta, fetal liver, spleen, thymus and tonsil. The expression in a variety of immune tissues and similarity to IL-1Ra suggest a role of IL-38 as a IL-1 family receptor antagonist. Il-38 inhibits IL-36 signaling by binding to IL-1R6. IL-38 (aa 20-152) is released from apoptotic cells to limit inflammatory macrophage and downstream Th17 activation by blocking IL1RAPL1 (Interleukin-1 receptor accessory protein-like 1, TIGIRR-2) signaling. IL-38 is unregulated during some autoimmune diseases such as Systemic Lupus Erythematosus.
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