TLR7 抗体 (AA 500-900) (FITC)
-
- 抗原 See all TLR7 抗体
- TLR7 (Toll-Like Receptor 7 (TLR7))
-
抗原表位
- AA 500-900
-
适用
- 人
-
宿主
- 小鼠
-
克隆类型
- 单克隆
-
标记
- This TLR7 antibody is conjugated to FITC
-
应用范围
- Flow Cytometry (FACS)
- 特异性
- Recognizes human TLR7.
- 交叉反应
- 人
- 纯化方法
- Protein G purified.
- 免疫原
- Recombinant human TLR7 protein (aa 500-900).
- 克隆位点
- ABM2C27
- 亚型
- IgG1
- Top Product
- Discover our top product TLR7 Primary Antibody
-
anti-Toll-Like Receptor 7 (TLR7) (AA 30-230) antibody
TLR7 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Toll-Like Receptor 7 (TLR7) (AA 1020-1047), (C-Term) antibodyTLR7 适用: 人, 小鼠, 大鼠 WB, IHC (p), ICC, IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Toll-Like Receptor 7 (TLR7) (AA 461-560) antibodyTLR7 适用: 人, 小鼠, 大鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-Toll-Like Receptor 7 (TLR7) (AA 465-483) antibodyTLR7 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Toll-Like Receptor 7 (TLR7) antibodyTLR7 适用: 人, 小鼠, 大鼠 WB, FACS, IHC (p), ICC, IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Toll-Like Receptor 7 (TLR7) (AA 27-126) antibodyTLR7 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 2C9 unconjugated
anti-Toll-Like Receptor 7 (TLR7) (AA 900-950) antibodyTLR7 适用: 人, 猴 WB, IHC, FACS, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Toll-Like Receptor 7 (TLR7) (AA 706-728) antibody (FITC)TLR7 适用: 人, 小鼠 FACS 宿主: 兔 Polyclonal FITC
anti-Toll-Like Receptor 7 (TLR7) (AA 890-1037) antibodyTLR7 适用: 小鼠 WB, IHC, ICC, IP 宿主: 兔 Polyclonal unconjugated
anti-Toll-Like Receptor 7 (TLR7) (AA 27-126) antibodyTLR7 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 3G6 unconjugated
-
- 限制
- 仅限研究用
-
- 状态
- Liquid
- 浓度
- Lot specific
- 缓冲液
- In 10 mM TRIS containing 150 mM NaCl and 0.05 % sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C
- 储存方法
-
Short Term Storage: +4°C
Long Term Storage: +4°C
Stable for at least 6 months after receipt when stored at +4°C. - 有效期
- 6 months
-
- 抗原
- TLR7 (Toll-Like Receptor 7 (TLR7))
- 别名
- TLR7 (TLR7 产品)
- 别名
- TLR7-like antibody, RGD1563357 antibody, toll like receptor 7 antibody, toll-like receptor 7 antibody, TLR7 antibody, Tlr7 antibody
- 背景
- TLR7 (Toll-like Receptor 7) is a member of the TLR (Toll-like receptor) family that plays a fundamental role in pathogen recognition and activation of innate immunity. TLR7 is a nucleotide-sensing TLR. TLR7 and TLR8 recognize single-stranded RNA (ssRNA) sequences containing GU-rich or poly-U sequences as their natural ligands, and they are also activated by synthetic small-molecular-weight compounds of the imidazoquinoline family. Both TLR7 and TLR8 signal via MYD88 and TRAF6, leading to NF-kappaB and antiviral factor, such as IRF family activation, cytokine secretion and the inflammatory response. They are localized intracellularly to endosomal membranes and act as potent activators of innate immune responses upon viral infection. The TLR7 gene is predominantly expressed in lung, placenta and spleen, and lies in close proximity to TLR8 on chromosome X. TLR7 has been shown to play a significant role in the pathogenesis of autoimmune disorders such as Systemic Lupus Erythematosus (SLE) as well as in the regulation of antiviral immunity. Recently, small molecule TLR7/8 agonists have demonstrated potential as vaccine adjuvants, since they directly activate APCs and can enhance both humoral and cellular immune responses, especially Th1 responses. This makes the TLR7/8 signaling pathways interesting therapeutic targets.
- 途径
- TLR signaling, Activation of Innate immune Response, Toll-Like Receptors Cascades
-
