TLR10 抗体 (AA 100-369)
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- 抗原 See all TLR10 抗体
- TLR10 (Toll-Like Receptor 10 (TLR10))
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抗原表位
- AA 100-369
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适用
- 人
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This TLR10 antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 交叉反应
- 人
- 纯化方法
- Protein G purified.
- 免疫原
- Recombinant human TLR10 protein (aa 100-369).
- 克隆位点
- ABM3C85
- 亚型
- IgG2a
- Top Product
- Discover our top product TLR10 Primary Antibody
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anti-Toll-Like Receptor 10 (TLR10) (AA 1-811) antibody
TLR10 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 2A11 unconjugated
anti-Toll-Like Receptor 10 (TLR10) (AA 20-250) antibodyTLR10 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Toll-Like Receptor 10 (TLR10) (AA 617-784) antibodyTLR10 适用: 人 WB, IHC, ICC 宿主: 兔 Polyclonal unconjugated
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- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- Lot specific
- 缓冲液
- In PBS containing 0.05 % BSA and 0.05 % sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
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Short Term Storage: +4°C
Long Term Storage: -20°C
Stable for at least 1 year after receipt when stored at -20°C. Stable for at least 6 months after receipt when stored at +4°C. - 有效期
- 12 months
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- 抗原
- TLR10 (Toll-Like Receptor 10 (TLR10))
- 别名
- TLR10 (TLR10 产品)
- 别名
- TLR10 antibody, CD290 antibody, toll like receptor 10 antibody, toll-like receptor 10 antibody, TLR10 antibody, Tlr10 antibody
- 背景
- TLR10 (Toll-like Receptor10) is an orphan member of the TLR family and is the only pattern-recognition receptor without known ligand specificity and biological function. TLR10 is predominantly expressed in tissues rich in immune cells, such as spleen, lymph node, thymus, tonsil, and lung. This protein plays a role in innate immune responses following viral infection. Influenza virus infection increased TLR10 expression and TLR10 contributed to innate immune sensing of viral infection leading to cytokine induction, including proinflammatory cytokines and interferons. Blocking TLR10 by antagonistic antibodies enhanced proinflammatory cytokine production, including IL-1beta specifically after exposure to TLR2 ligands. Like TLR1 and TLR6, TLR10 has also been shown to form a heterodimer complex with TLR2 during Helicobacter pylori infection and that it could be involved in the recognition of FSL-1, LPS and flagellin. TLR10 is an important innate immune sensor of viral infection with a role in innate immune defense and immunopathology following viral and bacterial pathogen infection.
- 途径
- TLR signaling, Activation of Innate immune Response, Toll-Like Receptors Cascades
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