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IL1F9 抗体

IL1F9 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal Jussy-1 unconjugated
产品编号 ABIN5564239
发货至: 中国
  • 抗原 See all IL1F9 抗体
    IL1F9 (Interleukin 1 Family Member 9 (IL1F9))
    适用
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    宿主
    • 25
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    小鼠
    克隆类型
    • 25
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    单克隆
    标记
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    This IL1F9 antibody is un-conjugated
    应用范围
    • 25
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    Western Blotting (WB), ELISA
    特异性
    Recognizes human IL-36gamma.
    交叉反应
    纯度
    >95 % (SDS-PAGE)
    免疫原
    Recombinant human IL-36gamma.
    克隆位点
    Jussy-1
    亚型
    IgG1
    Top Product
    Discover our top product IL1F9 Primary Antibody
  • 限制
    仅限研究用
  • 状态
    Liquid
    浓度
    Lot specific
    缓冲液
    In PBS containing 10 % glycerol and 0.02 % sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Short Term Storage: +4°C
    Long Term Storage: -20°C
    Stable for at least 1 year after receipt when stored at -20°C.
    有效期
    12 months
  • 抗原
    IL1F9 (Interleukin 1 Family Member 9 (IL1F9))
    别名
    IL-36gamma (IL1F9 产品)
    别名
    IL-1F9 antibody, IL-1H1 antibody, IL-1RP2 antibody, IL1E antibody, IL1F9 antibody, IL1H1 antibody, IL1RP2 antibody, Il36g antibody, Il1f9 antibody, RGD1563019 antibody, IL36G antibody, interleukin 36 gamma antibody, interleukin 1 family, member 9 antibody, interleukin 36, gamma antibody, interleukin-36 gamma antibody, IL36G antibody, Il1f9 antibody, Il36g antibody, LOC100065031 antibody
    背景
    IL-36alpha (IL-1F6), IL-36beta (IL-1F8) and IL-36gamma (IL-1F9) bind to IL-36R (IL-1Rrp2) and IL-1RAcP, activating similar intracellular signals as IL-1 and are inhibited by IL-36Ra. The expression of IL-36 cytokines has been shown to occur at different sites including the lung and skin and can be derived from diverse cell types including keratinocytes, bronchial epithelium as well as macrophages, monocytes and different T cell subsets. IL-36 family members induce the production of proinflammatory cytokines, including IL-12, IL-1beta, IL-6, TNF-alpha and IL-23 in BMDC and CD4 T cells, thus promoting neutrophil influx, dendritic cell (DC) activation, polarization of T helper type 1 (Th1) and IL-17-producing T cells (alphabeta T cells and gammadelta T cells) and keratinocyte proliferation. These cytokines may represent potential targets for immune-mediated inflammatory conditions or, alternatively, could be used as adjuvants in vaccination. IL-36gamma is also induced in the lung in various models of asthma and can be produced by bronchial epithelial cells in response to viral infection, smoke or inflammatory cytokines.
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