Glycogen Synthase 1 抗体 (pSer641)
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- 抗原 See all Glycogen Synthase 1 (GYS1) 抗体
- Glycogen Synthase 1 (GYS1) (Glycogen Synthase 1 (Muscle) (GYS1))
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抗原表位
- pSer641
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适用
- 人, 小鼠, 大鼠
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宿主
- 兔
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克隆类型
- 单克隆
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标记
- This Glycogen Synthase 1 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc))
- 交叉反应
- 人, 小鼠, 大鼠
- 纯化方法
- Purified by Protein A.
- 免疫原
- Synthetic peptide derived from human Glycogen synthase 1(S641), around 630-680aa (phospho S641).
- 克隆位点
- 10C1
- 亚型
- IgG
- Top Product
- Discover our top product GYS1 Primary Antibody
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- 应用备注
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WB 1:300-5000
IHC-P 1:200-400
IF(ICC) 1:50-200 - 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 μg/μL
- 缓冲液
- Aqueous buffered solution containing 1xTBS ( pH 7.4), 1 % BSA, 40 %Glycerol and 0.05 % Sodium Azide.
- 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
- 有效期
- 12 months
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- 抗原
- Glycogen Synthase 1 (GYS1) (Glycogen Synthase 1 (Muscle) (GYS1))
- 别名
- Glycogen synthase 1 (GYS1 产品)
- 别名
- GSY antibody, GYS antibody, GYS1 antibody, zgc:63701 antibody, GYS2 antibody, Gys3 antibody, MGS antibody, glycogen synthase 1 antibody, glycogen synthase 1 (muscle) antibody, glycogen synthase 1, muscle antibody, GYS1 antibody, gys1 antibody, Gys1 antibody
- 背景
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Synonyms: Glycogen synthase 1 phospho S640, Glycogen synthase 1 phospho Ser640, p-Glycogen synthase 1 S640, Glycogen synthase 1 muscle, Glycogen synthase 1, GSY, GYS, GYS1, EC 2.4.1.11, Glycogen synthase1, GYS 1, Starchsynthase muscle, UDP glucose glycogen glucosyltransferase, GYS1_HUMAN, Glycogen [starch] synthase, muscl.
Background: Glycogen Synthase (GS) is a key enzyme in the regulation of glycogen metabolism. GS catalyzes the incorporation of UDP-glucose incorporation into glycogen. The activity of glycogen synthase is regulated by hormonal stimuli (insulin, catecholamines and glucagons) and non-hormonal stimuli (blood glucose level and exercise). Two main isoforms of mammalian GS are designated as muscle (glycogen synthase 1) and liver (glycogen synthase 2). Most tissues express glycogen synthase 1, whereas glycogen synthase 2 appears to be tissue-specific. The two isoforms have 70 % identical amino acid sequence. Glycogen synthase can be phosphorylated by multiple kinases including glycogen synthase kinase-3 (GSK-3), mitogen-activated protein kinase-related protein kinase (DYRK), and SAPK2b/p38b which leads to its inactivation.
- 基因ID
- 2997
- UniProt
- P13807
- 途径
- PI3K-Akt Signaling, AMPK Signaling, Cellular Glucan Metabolic Process
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