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Cytochrome C 抗体

CYCS 适用: 人, 大鼠, 小鼠 WB, IHC (p), IF (p), IF (cc) 宿主: 兔 Monoclonal 1F10 unconjugated
产品编号 ABIN5557297
发货至: 中国
  • 抗原 See all Cytochrome C (CYCS) 抗体
    Cytochrome C (CYCS) (Cytochrome C, Somatic (CYCS))
    适用
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    人, 大鼠, 小鼠
    宿主
    • 83
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    克隆类型
    • 80
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    • 1
    单克隆
    标记
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    This Cytochrome C antibody is un-conjugated
    应用范围
    • 123
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    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunofluorescence (Cultured Cells) (IF (cc))
    交叉反应
    人, 小鼠, 大鼠
    纯化方法
    Purified by Protein A.
    免疫原
    Recombinant human Cytochrome C protein, full length.
    克隆位点
    1F10
    亚型
    IgG
    Top Product
    Discover our top product CYCS Primary Antibody
  • 应用备注
    WB 1:300-5000
    IHC-P 1:200-400
    IF(IHC-P) 1:50-200
    IF(ICC) 1:50-200
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 μg/μL
    缓冲液
    Aqueous buffered solution containing 1xTBS ( pH 7.4), 1 % BSA, 40 %Glycerol and 0.05 % Sodium Azide.
    储存液
    ProClin
    注意事项
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
    有效期
    12 months
  • 抗原
    Cytochrome C (CYCS) (Cytochrome C, Somatic (CYCS))
    别名
    Cytochrome C (CYCS 产品)
    背景

    Synonyms: CYC, HCS, THC4, Cytochrome c, CYCS

    Background: Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. Plays a role in apoptosis. Suppression of the anti-apoptotic members or activation of the pro-apoptotic members of the Bcl-2 family leads to altered mitochondrial membrane permeability resulting in release of cytochrome c into the cytosol. Binding of cytochrome c to Apaf-1 triggers the activation of caspase-9, which then accelerates apoptosis by activating other caspases.

    基因ID
    54205
    UniProt
    P99999
    途径
    Apoptosis, Caspase Cascade in Apoptosis, Positive Regulation of Endopeptidase Activity
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