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DOC2A 抗体 (AA 652-749)

DOC2A 适用: 人 ELISA, FACS, ICC 宿主: 小鼠 Monoclonal 2H7C4 unconjugated
产品编号 ABIN5542714
发货至: 中国
  • 抗原 See all DOC2A 抗体
    DOC2A (Double C2-Like Domains, alpha (DOC2A))
    抗原表位
    • 7
    • 7
    • 6
    • 6
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 652-749
    适用
    • 22
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    宿主
    • 17
    • 3
    • 2
    • 1
    小鼠
    克隆类型
    • 21
    • 2
    单克隆
    标记
    • 13
    • 2
    • 2
    • 2
    • 2
    • 2
    This DOC2A antibody is un-conjugated
    应用范围
    • 20
    • 16
    • 13
    • 12
    • 2
    • 1
    • 1
    • 1
    ELISA, Flow Cytometry (FACS), Immunocytochemistry (ICC)
    原理
    DOC2 Antibody
    纯化方法
    Purified antibody
    免疫原
    Purified recombinant fragment of human DOC2 (AA: 652-749) expressed in E. Coli.
    克隆位点
    2H7C4
    亚型
    IgG1
  • 应用备注

    ELISA: 1/10000

    FCM: 1/200 - 1/400

    ICC: 1/200 - 1/1000

    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Purified antibody in PBS with 0.05 % sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
  • 抗原
    DOC2A (Double C2-Like Domains, alpha (DOC2A))
    别名
    DOC2 (DOC2A 产品)
    别名
    DOC2A antibody, doc2-A antibody, Doc2 antibody, double C2 domain alpha antibody, double C2-like domains, alpha antibody, double C2, alpha antibody, DOC2A antibody, doc2a antibody, Doc2a antibody
    背景

    Description: This gene encodes a mitogen-responsive phosphoprotein. It is expressed in normal ovarian epithelial cells, but is down-regulated or absent from ovarian carcinoma cell lines, suggesting its role as a tumor suppressor. This protein binds to the SH3 domains of GRB2, an adaptor protein that couples tyrosine kinase receptors to SOS (a guanine nucleotide exchange factor for Ras), via its C-terminal proline-rich sequences, and may thus modulate growth factor/Ras pathways by competing with SOS for binding to GRB2. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

    Aliases: DAB2, DOC-2

    分子量
    82.4kDa
    基因ID
    1601
    HGNC
    5899
    UniProt
    P98082
    途径
    Synaptic Vesicle Exocytosis
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