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Phospholipase C gamma 1 抗体 (AA 39-181)

PLCG1 适用: 人 ELISA, FACS 宿主: 小鼠 Monoclonal 2F3E10 unconjugated
产品编号 ABIN5542683
发货至: 中国
  • 抗原 See all Phospholipase C gamma 1 (PLCG1) 抗体
    Phospholipase C gamma 1 (PLCG1) (phospholipase C, gamma 1 (PLCG1))
    抗原表位
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    AA 39-181
    适用
    • 138
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    • 21
    • 8
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    • 1
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    宿主
    • 149
    • 21
    小鼠
    克隆类型
    • 141
    • 29
    单克隆
    标记
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    This Phospholipase C gamma 1 antibody is un-conjugated
    应用范围
    • 115
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    ELISA, Flow Cytometry (FACS)
    原理
    PLCG1 Antibody
    纯化方法
    Purified antibody
    免疫原
    Purified recombinant fragment of human PLCG1 (AA: 39-181) expressed in E. Coli.
    克隆位点
    2F3E10
    亚型
    IgG2a
    Top Product
    Discover our top product PLCG1 Primary Antibody
  • 应用备注

    ELISA: 1/10000

    FCM: 1/200 - 1/400

    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Purified antibody in PBS with 0.05 % sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
  • 抗原
    Phospholipase C gamma 1 (PLCG1) (phospholipase C, gamma 1 (PLCG1))
    别名
    PLCG1 (PLCG1 产品)
    别名
    NCKAP3 antibody, PLC-II antibody, PLC1 antibody, PLC148 antibody, PLCgamma1 antibody, plc1 antibody, nckap3 antibody, plc-ii antibody, plc148 antibody, plcgamma1 antibody, PPLCA antibody, AI894140 antibody, Cded antibody, Plc-1 antibody, Plc-gamma1 antibody, Plcg-1 antibody, fj46f04 antibody, wu:fj46f04 antibody, wu:fj57a05 antibody, phospholipase C gamma 1 antibody, phospholipase C gamma 1 L homeolog antibody, 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 antibody, phospholipase C, gamma 1 antibody, PLCG1 antibody, plcg1.L antibody, LOC100633163 antibody, Plcg1 antibody, plcg1 antibody
    背景

    Description: The protein encoded by this gene catalyzes the formation of inositol 1,4,5-trisphosphate and diacylglycerol from phosphatidylinositol 4,5-bisphosphate. This reaction uses calcium as a cofactor and plays an important role in the intracellular transduction of receptor-mediated tyrosine kinase activators. For example, when activated by SRC, the encoded protein causes the Ras guanine nucleotide exchange factor RasGRP1 to translocate to the Golgi, where it activates Ras. Also, this protein has been shown to be a major substrate for heparin-binding growth factor 1 (acidic fibroblast growth factor)-activated tyrosine kinase. Two transcript variants encoding different isoforms have been found for this gene.

    Aliases: PLC1, NCKAP3, PLC-II, PLC148, PLCgamma1

    分子量
    148.5kDa
    基因ID
    5335
    HGNC
    5335
    UniProt
    P19174
    途径
    RTK signaling, WNT signaling, TCR Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Thyroid Hormone Synthesis, Inositol Metabolic Process, Myometrial Relaxation and Contraction, Regulation of Muscle Cell Differentiation, Regulation of G-Protein Coupled Receptor Protein Signaling, Skeletal Muscle Fiber Development, G-protein mediated Events, Signaling Events mediated by VEGFR1 and VEGFR2, Interaction of EGFR with phospholipase C-gamma, VEGFR1 Specific Signals, VEGF Signaling
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