WASP 抗体 (AA 57-170)
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- 抗原 See all WASP (WAS) 抗体
- WASP (WAS) (Wiskott-Aldrich Syndrome (Eczema-thrombocytopenia) (WAS))
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抗原表位
- AA 57-170
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适用
- 人
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This WASP antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Flow Cytometry (FACS)
- 纯化方法
- purified
- 免疫原
- Purified recombinant fragment of human WAS (AA: 57-170) expressed in E. coli.
- 克隆位点
- 7B10E4
- 亚型
- IgG2a
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- 应用备注
- ELISA: 1:10000, WB: 1:500 - 1:2000, IHC: 1:200 - 1:1000, FCM: 1:200 - 1:400
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- Purified antibody in PBS with 0.05 % sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C/-20 °C
- 储存方法
- 4°C, -20°C for long term storage
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- 抗原
- WASP (WAS) (Wiskott-Aldrich Syndrome (Eczema-thrombocytopenia) (WAS))
- 别名
- WAS (WAS 产品)
- 别名
- IMD2 antibody, SCNX antibody, THC antibody, THC1 antibody, WASP antibody, U42471 antibody, WASp antibody, Wasp antibody, imd2 antibody, thc antibody, thc1 antibody, was antibody, wasp antibody, wu:fk81c08 antibody, zgc:64164 antibody, Wiskott-Aldrich syndrome antibody, neural Wiskott-Aldrich syndrome protein antibody, wiskott-aldrich syndrome protein antibody, Wiskott-Aldrich syndrome L homeolog antibody, Wiskott-Aldrich syndrome (eczema-thrombocytopenia) b antibody, WAS antibody, LOC5578888 antibody, CpipJ_CPIJ006699 antibody, Was antibody, was.L antibody, wasb antibody
- 背景
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Description: The Wiskott-Aldrich syndrome (WAS) family of proteins share similar domain structure, and are involved in transduction of signals from receptors on the cell surface to the actin cytoskeleton. The presence of a number of different motifs suggests that they are regulated by a number of different stimuli, and interact with multiple proteins. Recent studies have demonstrated that these proteins, directly or indirectly, associate with the small GTPase, Cdc42, known to regulate formation of actin filaments, and the cytoskeletal organizing complex, Arp2/3. Wiskott-Aldrich syndrome is a rare, inherited, X-linked, recessive disease characterized by immune dysregulation and microthrombocytopenia, and is caused by mutations in the WAS gene. The WAS gene product is a cytoplasmic protein, expressed exclusively in hematopoietic cells, which show signalling and cytoskeletal abnormalities in WAS patients. A transcript variant arising as a result of alternative promoter usage, and containing a different 5' UTR sequence, has been described, however, its full-length nature is not known.
Aliases: THC, IMD2, SCNX, THC1, WASP
- 分子量
- 53 kDa
- 基因ID
- 7454
- HGNC
- 7454
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