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RAD50 抗体 (AA 228-359)

RAD50 适用: 人 WB, IHC, ELISA, FACS 宿主: 小鼠 Monoclonal 3D2G10 unconjugated
产品编号 ABIN5542671
发货至: 中国
  • 抗原 See all RAD50 抗体
    RAD50 (RAD50 Homolog (S. Cerevisiae) (RAD50))
    抗原表位
    • 16
    • 8
    • 8
    • 7
    • 6
    • 5
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    AA 228-359
    适用
    • 54
    • 51
    • 18
    • 5
    • 5
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    宿主
    • 66
    • 4
    小鼠
    克隆类型
    • 65
    • 5
    单克隆
    标记
    • 34
    • 7
    • 4
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This RAD50 antibody is un-conjugated
    应用范围
    • 59
    • 23
    • 15
    • 15
    • 13
    • 13
    • 10
    • 10
    • 6
    • 5
    • 3
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Flow Cytometry (FACS)
    原理
    RAD50 Antibody
    纯化方法
    Purified antibody
    免疫原
    Purified recombinant fragment of human RAD50 (AA: 228-359) expressed in E. Coli.
    克隆位点
    3D2G10
    亚型
    IgG2a
    Top Product
    Discover our top product RAD50 Primary Antibody
  • 应用备注

    ELISA: 1/10000

    FCM: 1/200 - 1/400

    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Purified antibody in PBS with 0.05 % sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
  • 抗原
    RAD50 (RAD50 Homolog (S. Cerevisiae) (RAD50))
    别名
    RAD50 (RAD50 产品)
    别名
    NBSLD antibody, RAD502 antibody, hRad50 antibody, Mrell antibody, Rad50l antibody, 6339 antibody, CG6339 antibody, Dmel\\CG6339 antibody, Dmrad50 antibody, RAD50 antibody, Rad50 antibody, ATRAD50 antibody, DNA REPAIR-RECOMBINATION PROTEIN antibody, F22D22.28 antibody, F22D22_28 antibody, SPAP4C9.01c antibody, im:6906849 antibody, si:ch211-79h18.3 antibody, RAD50 double strand break repair protein antibody, CG6339 gene product from transcript CG6339-RE antibody, RAD50 homolog, double strand break repair protein L homeolog antibody, rad50 antibody, DNA repair protein RAD50 antibody, RAD50 homolog, double strand break repair protein antibody, DNA repair-recombination protein (RAD50) antibody, MRX complex DNA-binding subunit antibody, DNA repair protein Rad50 antibody, RAD50 recombination protein antibody, Rad50 DNA repair/recombination protein antibody, DNA repair protein rad-50 antibody, RAD50 antibody, Rad50 antibody, rad50 antibody, rad50.L antibody, LOC658288 antibody, LOC726642 antibody, rad-50 antibody
    背景

    Description: The protein encoded by this gene is highly similar to Saccharomyces cerevisiae Rad50, a protein involved in DNA double-strand break repair. This protein forms a complex with MRE11 and NBS1. The protein complex binds to DNA and displays numerous enzymatic activities that are required for nonhomologous joining of DNA ends. This protein, cooperating with its partners, is important for DNA double-strand break repair, cell cycle checkpoint activation, telomere maintenance, and meiotic recombination. Knockout studies of the mouse homolog suggest this gene is essential for cell growth and viability. Mutations in this gene are the cause of Nijmegen breakage syndrome-like disorder.

    Aliases: NBSLD, RAD502, hRad50

    分子量
    154kDa
    基因ID
    10111
    HGNC
    10111
    UniProt
    Q92878
    途径
    DNA Damage Repair, Protein targeting to Nucleus
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