RAD50 抗体 (AA 228-359)
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- 抗原 See all RAD50 抗体
- RAD50 (RAD50 Homolog (S. Cerevisiae) (RAD50))
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抗原表位
- AA 228-359
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适用
- 人
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This RAD50 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Flow Cytometry (FACS)
- 原理
- RAD50 Antibody
- 纯化方法
- Purified antibody
- 免疫原
- Purified recombinant fragment of human RAD50 (AA: 228-359) expressed in E. Coli.
- 克隆位点
- 3D2G10
- 亚型
- IgG2a
- Top Product
- Discover our top product RAD50 Primary Antibody
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- 应用备注
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ELISA: 1/10000
FCM: 1/200 - 1/400
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- Purified antibody in PBS with 0.05 % sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
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- 抗原
- RAD50 (RAD50 Homolog (S. Cerevisiae) (RAD50))
- 别名
- RAD50 (RAD50 产品)
- 背景
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Description: The protein encoded by this gene is highly similar to Saccharomyces cerevisiae Rad50, a protein involved in DNA double-strand break repair. This protein forms a complex with MRE11 and NBS1. The protein complex binds to DNA and displays numerous enzymatic activities that are required for nonhomologous joining of DNA ends. This protein, cooperating with its partners, is important for DNA double-strand break repair, cell cycle checkpoint activation, telomere maintenance, and meiotic recombination. Knockout studies of the mouse homolog suggest this gene is essential for cell growth and viability. Mutations in this gene are the cause of Nijmegen breakage syndrome-like disorder.
Aliases: NBSLD, RAD502, hRad50
- 分子量
- 154kDa
- 基因ID
- 10111
- HGNC
- 10111
- UniProt
- Q92878
- 途径
- DNA Damage Repair, Protein targeting to Nucleus
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