SSH1 抗体 (AA 1032-1044)
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- 抗原 See all SSH1 抗体
- SSH1 (Slingshot Homolog 1 (SSH1))
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抗原表位
- AA 1032-1044
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适用
- 人
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This SSH1 antibody is un-conjugated
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应用范围
- ELISA, Immunohistochemistry (IHC), Flow Cytometry (FACS)
- 原理
- SLINGSHOT-1L Antibody
- 纯化方法
- Purified antibody
- 免疫原
- Synthesized peptide fragment of human SLINGSHOT-1L (AA: 1032-1044 ) expressed in E. Coli.
- 克隆位点
- 6C11G9
- 亚型
- IgG1
- Top Product
- Discover our top product SSH1 Primary Antibody
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- 应用备注
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ELISA: 1/10000
FCM: 1/200 - 1/400
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- Purified antibody in PBS with 0.05 % sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
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- 抗原
- SSH1 (Slingshot Homolog 1 (SSH1))
- 别名
- SLINGSHOT-1L (SSH1 产品)
- 别名
- AW551225 antibody, Gm1394 antibody, Gm1395 antibody, SSH-1 antibody, mSSH-1L antibody, SSH1L antibody, slingshot homolog 1 (Drosophila) antibody, slingshot protein phosphatase 1 antibody, Ssh1 antibody, SSH1 antibody
- 背景
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Description: The protein encoded by this gene belongs to the slingshot homolog (SSH) family of phosphatases, which regulate actin filament dynamics. The SSH proteins dephosphorylate and activate the actin binding/depolymerizing factor cofilin, which subsequently binds to actin filaments and stimulates their disassembly. Cofilin is inactivated by kinases such as LIM domain kinase-1 (LIMK1), which may also be dephosphorylated and inactivated by SSH proteins. The SSH family thus appears to play a role in actin dynamics by reactivating cofilin proteins. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.
Aliases: SSH1,SSH1L
- 分子量
- 115.5kDa
- 基因ID
- 54434
- HGNC
- 54434
- UniProt
- Q8WYL5
- 途径
- CXCR4-mediated Signaling Events
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