MMP14 抗体 (AA 112-246)
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- 抗原 See all MMP14 抗体
- MMP14 (Matrix Metallopeptidase 14 (Membrane-inserted) (MMP14))
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抗原表位
- AA 112-246
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适用
- 人
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This MMP14 antibody is un-conjugated
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应用范围
- ELISA, Immunohistochemistry (IHC), Flow Cytometry (FACS)
- 原理
- MMP14 Antibody
- 纯化方法
- Purified antibody
- 免疫原
- Purified recombinant fragment of human MMP14 (AA: 112-246) expressed in E. Coli.
- 克隆位点
- 6A11D1
- 亚型
- IgG1
- Top Product
- Discover our top product MMP14 Primary Antibody
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- 应用备注
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ELISA: 1/10000
FCM: 1/200 - 1/400
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- Purified antibody in PBS with 0.05 % sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
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- 抗原
- MMP14 (Matrix Metallopeptidase 14 (Membrane-inserted) (MMP14))
- 别名
- MMP14 (MMP14 产品)
- 背景
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Description: Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. However, the protein encoded by this gene is a member of the membrane-type MMP (MT-MMP) subfamily, each member of this subfamily contains a potential transmembrane domain suggesting that these proteins are expressed at the cell surface rather than secreted. This protein activates MMP2 protein, and this activity may be involved in tumor invasion.
Aliases: MMP-14, MMP-X1, MT-MMP, MT1MMP, MTMMP1, WNCHRS, MT1-MMP, MT-MMP 1
- 分子量
- 65.9kDa
- 基因ID
- 4323
- HGNC
- 4323
- UniProt
- P50281
- 途径
- Autophagy
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