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CFHR5 抗体 (AA 344-569)

CFHR5 适用: 人, 小鼠 WB, ELISA, FACS, IHC, ICC 宿主: 小鼠 Monoclonal 3A10A5 unconjugated
产品编号 ABIN5542640
发货至: 中国
  • 抗原 See all CFHR5 抗体
    CFHR5 (Complement Factor H-Related 5 (CFHR5))
    抗原表位
    • 7
    • 6
    • 6
    • 6
    • 4
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    AA 344-569
    适用
    人, 小鼠
    宿主
    • 25
    • 11
    小鼠
    克隆类型
    • 26
    • 10
    单克隆
    标记
    • 16
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This CFHR5 antibody is un-conjugated
    应用范围
    • 26
    • 18
    • 15
    • 14
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB), ELISA, Flow Cytometry (FACS), Immunohistochemistry (IHC), Immunocytochemistry (ICC)
    纯化方法
    purified
    免疫原
    Purified recombinant fragment of human CFHR5 (AA: 344-569) expressed in E. coli.
    克隆位点
    3A10A5
    亚型
    IgG2a
    Top Product
    Discover our top product CFHR5 Primary Antibody
  • 应用备注
    ELISA: 1:10000, WB: 1:500 - 1:2000, IHC: 1:200 - 1:1000, ICC: 1:200 - 1:1000, FCM: 1:200 - 1:400
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Purified antibody in PBS with 0.05 % sodium azide
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C/-20 °C
    储存方法
    4°C, -20°C for long term storage
  • 抗原
    CFHR5 (Complement Factor H-Related 5 (CFHR5))
    别名
    CFHR5 (CFHR5 产品)
    别名
    CFHL5 antibody, CFHR5D antibody, FHR-5 antibody, FHR5 antibody, complement factor H related 5 antibody, CFHR5 antibody
    背景

    Description: This gene is a member of a small complement factor H (CFH) gene cluster on chromosome 1. Each member of this gene family contains multiple short consensus repeats (SCRs) typical of regulators of complement activation. The protein encoded by this gene has nine SCRs with the first two repeats having heparin binding properties, a region within repeats 5-7 having heparin binding and C reactive protein binding properties, and the C-terminal repeats being similar to a complement component 3 b (C3b) binding domain. This protein co-localizes with C3, binds C3b in a dose-dependent manner, and is recruited to tissues damaged by C-reactive protein. Allelic variations in this gene have been associated, but not causally linked, with two different forms of kidney disease: membranoproliferative glomerulonephritis type II (MPGNII) and hemolytic uraemic syndrome (HUS).,

    Aliases: FHR5, CFHL5, FHR-5, CFHR5D

    分子量
    64.4 kDa
    基因ID
    81494
    HGNC
    81494
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