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HLA-DRA 抗体 (AA 26-254)

HLA-DRA 适用: 人 WB, FACS, ELISA, ICC 宿主: 小鼠 Monoclonal 1C11A5 unconjugated
产品编号 ABIN5542623
发货至: 中国
  • 抗原 See all HLA-DRA 抗体
    HLA-DRA (HLA Class II DR alpha (HLA-DRA))
    抗原表位
    • 8
    • 5
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    AA 26-254
    适用
    • 85
    • 17
    • 10
    • 10
    • 9
    • 9
    • 3
    • 2
    • 2
    • 1
    宿主
    • 57
    • 42
    • 2
    • 1
    小鼠
    克隆类型
    • 59
    • 43
    单克隆
    标记
    • 49
    • 12
    • 5
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    This HLA-DRA antibody is un-conjugated
    应用范围
    • 45
    • 43
    • 34
    • 30
    • 15
    • 10
    • 10
    • 9
    • 9
    • 3
    • 3
    • 3
    • 1
    • 1
    • 1
    Western Blotting (WB), Flow Cytometry (FACS), ELISA, Immunocytochemistry (ICC)
    原理
    HLA-DRA Antibody
    纯化方法
    Purified antibody
    免疫原
    Purified recombinant fragment of human HLA-DRA (AA: 26-254) expressed in E. Coli.
    克隆位点
    1C11A5
    亚型
    IgG2b
  • 应用备注

    ELISA: 1/10000

    FCM: 1/200 - 1/400

    ICC: 1/100 - 1/500

    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Purified antibody in PBS with 0.05 % sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
  • 抗原
    HLA-DRA (HLA Class II DR alpha (HLA-DRA))
    别名
    HLA-DRA (HLA-DRA 产品)
    别名
    HLA-DRA1 antibody, MLRW antibody, DR-alpha antibody, HLA-DRA antibody, Mamu-DRA1 antibody, major histocompatibility complex, class II, DR alpha L homeolog antibody, major histocompatibility complex, class II, DR alpha antibody, hla-dra.L antibody, HLA-DRA antibody, MAMU-DRA antibody, BOLA-DRA antibody
    背景

    Description: HLA-DRA is one of the HLA class II alpha chain paralogues. This class II molecule is a heterodimer consisting of an alpha and a beta chain, both anchored in the membrane. It plays a central role in the immune system by presenting peptides derived from extracellular proteins. Class II molecules are expressed in antigen presenting cells (APC: B lymphocytes, dendritic cells, macrophages). The alpha chain is approximately 33-35 kDa and its gene contains 5 exons. Exon 1 encodes the leader peptide, exons 2 and 3 encode the two extracellular domains, and exon 4 encodes the transmembrane domain and the cytoplasmic tail. DRA does not have polymorphisms in the peptide binding part and acts as the sole alpha chain for DRB1, DRB3, DRB4 and DRB5.

    Aliases: MLRW, HLA-DRA1

    分子量
    28.6kDa
    基因ID
    3122
    HGNC
    3858
    UniProt
    P01903
    途径
    TCR Signaling, CXCR4-mediated Signaling Events, Human Leukocyte Antigen (HLA) in Adaptive Immune Response
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