PMS2 抗体 (AA 748-851)
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- 抗原 See all PMS2 抗体
- PMS2 (PMS2 Postmeiotic Segregation Increased 2 (S. Cerevisiae) (PMS2))
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抗原表位
- AA 748-851
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适用
- 人
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This PMS2 antibody is un-conjugated
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应用范围
- ELISA, Immunocytochemistry (ICC), Flow Cytometry (FACS)
- 原理
- PMS2 Antibody
- 纯化方法
- Purified antibody
- 免疫原
- Purified recombinant fragment of human PMS2 (AA: 748-851) expressed in E. Coli.
- 克隆位点
- 1E9D11
- 亚型
- IgG1
- Top Product
- Discover our top product PMS2 Primary Antibody
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- 应用备注
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ELISA: 1/10000
FCM: 1/200 - 1/400
ICC: 1/200 - 1/1000
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- Purified antibody in PBS with 0.05 % sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
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- 抗原
- PMS2 (PMS2 Postmeiotic Segregation Increased 2 (S. Cerevisiae) (PMS2))
- 别名
- PMS2 (PMS2 产品)
- 别名
- HNPCC4 antibody, PMS2CL antibody, PMSL2 antibody, AW555130 antibody, Pmsl2 antibody, PMS1 homolog 2, mismatch repair system component antibody, PMS1 homolog2, mismatch repair system component antibody, mismatch repair endonuclease PMS2 antibody, PMS2 antibody, Pms2 antibody, LOC463257 antibody, LOC107984056 antibody
- 背景
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Description: This gene is one of the PMS2 gene family members found in clusters on chromosome 7. The product of this gene is involved in DNA mismatch repair. It forms a heterodimer with MLH1 and this complex interacts with other complexes bound to mismatched bases. Mutations in this gene are associated with hereditary nonpolyposis colorectal cancer, Turcot syndrome, and are a cause of supratentorial primitive neuroectodermal tumors. Alternatively spliced transcript variants have been observed for this gene.
Aliases: PMSL2, HNPCC4, PMS2CL
- 分子量
- 95.8kDa
- 基因ID
- 5395
- HGNC
- 5395
- UniProt
- P54278
- 途径
- DNA Damage Repair, Production of Molecular Mediator of Immune Response
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