PDGFRB 抗体 (AA 33-133)
-
- 抗原 See all PDGFRB 抗体
- PDGFRB (Platelet Derived Growth Factor Receptor beta (PDGFRB))
-
抗原表位
- AA 33-133
-
适用
- 人
-
宿主
- 小鼠
-
克隆类型
- 单克隆
-
标记
- This PDGFRB antibody is un-conjugated
-
应用范围
- ELISA, Flow Cytometry (FACS)
- 原理
- PDGFRB Antibody
- 纯化方法
- Purified antibody
- 免疫原
- Purified recombinant fragment of human PDGFRB (AA: 33-133) expressed in E. Coli.
- 克隆位点
- 2G7B7
- 亚型
- IgG1
- Top Product
- Discover our top product PDGFRB Primary Antibody
-
-
- 应用备注
-
ELISA: 1/10000
FCM: 1/200 - 1/400
- 限制
- 仅限研究用
-
- 状态
- Liquid
- 缓冲液
- Purified antibody in PBS with 0.05 % sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
-
- 抗原
- PDGFRB (Platelet Derived Growth Factor Receptor beta (PDGFRB))
- 别名
- PDGFRB (PDGFRB 产品)
- 背景
-
Description: This gene encodes a cell surface tyrosine kinase receptor for members of the platelet-derived growth factor family. These growth factors are mitogens for cells of mesenchymal origin. The identity of the growth factor bound to a receptor monomer determines whether the functional receptor is a homodimer or a heterodimer, composed of both platelet-derived growth factor receptor alpha and beta polypeptides. This gene is flanked on chromosome 5 by the genes for granulocyte-macrophage colony-stimulating factor and macrophage-colony stimulating factor receptor, all three genes may be implicated in the 5-q syndrome. A translocation between chromosomes 5 and 12, that fuses this gene to that of the translocation, ETV6, leukemia gene, results in chronic myeloproliferative disorder with eosinophilia.
Aliases: IMF1, IBGC4, JTK12, PDGFR, CD140B, PDGFR1, PDGFR-1
- 分子量
- 124kDa
- 基因ID
- 5159
- HGNC
- 5159
- UniProt
- P09619
- 途径
- Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Inositol Metabolic Process, Glycosaminoglycan Metabolic Process, Smooth Muscle Cell Migration, Platelet-derived growth Factor Receptor Signaling
-